Naughton

When this treatment fails, dapsone and retinoids might be effective. Immunosuppressive agents and corticosteroids may be required to manage severe (systemic) disease activity. Prednisolone or pulse methylprednisolone are useful in treating relapses. Often, continued treatment with oral prednisolone

S. A., Á. M., R., 2006 .

Severe infections following leflunomide therapy for Rheumatoid Arthritis

Sethi, S. A., Khurana, 2006 .