Melanie J. Mittenbühler

Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin

B. Spiegelman, T. Dawson, V. Dawson, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues.

Edward T Chouchani, B. Spiegelman, S. Gygi, 2023, Cell metabolism.

Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo

Shu-Bing Qian, Jun Zhou, J. Brüning, 2020, Molecular metabolism.

Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between Obesity and Inflammation—Driven Liver and Colorectal Cancers

F. Wunderlich, C. Wunderlich, Lara Kern, 2018, Cancers.

Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma

J. Brüning, F. Wunderlich, Hans-Georg Sprenger, 2018, Molecular metabolism.

Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α.

B. Spiegelman, S. Gygi, P. Griffin, 2023, Molecular cell.

A comprehensive landscape of the zinc-regulated human proteome

Melanie J. Mittenbühler, Yizhi Sun, Edward T. Chouchani, 2024, bioRxiv.

Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition

Zhengye Liu, J. Ruas, J. Lanner, 2024, Molecular metabolism.