Meng Cao

Discovery of Novel Indole-based Allosteric Highly Potent ATX Inhibitors with Great in vivo Efficacy in Mouse Lung Fibrosis Model.

X. Zhai, Enlong Ma, Nan Jiang, 2020, Journal of medicinal chemistry.

Dual inhibitors of ASK1 and PDK1 kinases: Design, synthesis, molecular docking and mechanism studies of N-benzyl pyridine-2-one containing derivatives as anti-fibrotic agents.

Qianbin Li, Gaoyun Hu, Yuanyuan Cao, 2022, European journal of medicinal chemistry.

Structure-based design of 2,4-diaminopyrimidine derivatives bearing a pyrrolyl group as ALK and ROS1 inhibitors

X. Zhai, Nan Jiang, Daiying Zuo, 2020 .

Optimization and evaluation of novel tetrahydropyrido[4,3-d]pyrimidine derivatives as ATX inhibitors for cardiac and hepatic fibrosis.

X. Zhai, Junlong Zhang, Nan Jiang, 2019, European journal of medicinal chemistry.

Discovery and antitumor activity of Benzo[d]imidazol-containing 2,4-diarylaminopyrimidine analogues as ALK inhibitors with mutation-combating effects.

X. Zhai, Zheng Li, Ming-juan Guo, 2021, Bioorganic & medicinal chemistry.

An exploration of solvent-front region high affinity moiety leading to novel potent ALK & ROS1 dual inhibitors with mutant-combating effects.

X. Zhai, Daiying Zuo, Ming-juan Guo, 2019, Bioorganic & medicinal chemistry.

Pyrroformyl-containing 2,4-diaminopyrimidine derivatives as a new optimization strategy of ALK inhibitors combating mutations.

X. Zhai, Ming-juan Guo, Shangfei Wei, 2020, Bioorganic & medicinal chemistry.