David Goltzman

发表

Janet E. Henderson, David Goltzman, 2000 .

Interactions of PTH and PTHrP with the PTH/PTHrP Receptor and with Downstream Signaling Pathways: Exceptions That Provide the Rules

D. Goltzman, David Goltzman, D. Goltzman, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women

Jacques P. Brown, A. Silman, S. Cummings, 2007, Osteoporosis International.

Cloning and characterization of the promoter regions of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene: analysis of deoxyribonucleic acid from normal subjects and patients with pseudohypoparathyroidism type 1b.

John H. White, G. Hendy, D. Goltzman, 1997, The Journal of clinical endocrinology and metabolism.

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

Daniel L. Koller, D. Kiel, A. Uitterlinden, 2012, Nature Genetics.

Induction of parathyroid hormone-related peptide by the Ras oncogene: role of Ras farnesylation inhibitors as potential therapeutic agents for hypercalcemia of malignancy.

Morag Park, S. Rabbani, D. Goltzman, 1997, Cancer research.

Parathyroid hormone-like peptide in normal and neoplastic human endocrine tissues.

D. Drucker, S. Asa, D. Goltzman, 1990, The Journal of clinical endocrinology and metabolism.

The parathyroid hormone-like peptide gene is expressed in the normal and neoplastic human endocrine pancreas.

D. Drucker, S. Asa, D. Goltzman, 1989, Molecular endocrinology.

Dissection of differentially regulated (G+C)-rich promoters of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene.

G. Hendy, D. Goltzman, J. White, 2000, Endocrinology.

Developmental upregulation of human parathyroid hormone (PTH)/PTH-related peptide receptor gene expression from conserved and human-specific promoters.

John H. White, G. Hendy, D. Goltzman, 1998, The Journal of clinical investigation.

Role of mitogen-activated protein kinases in the induction of parathyroid hormone-related peptide.

S. Rabbani, D. Goltzman, J. Gladu, 2000, Cancer research.

Parathyroid Hormone-related Peptide Role of Mitogen-activated Protein Kinases in the Induction of Updated Version

S. Rabbani, D. Goltzman, J. Gladu, 2000 .

Isolation and characterization of multiple isoforms of the rat urokinase receptor in osteoblasts

S. Rabbani, D. Goltzman, K. Murthy, 1994, FEBS letters.

Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation

J. Reginster, R. Rizzoli, J. Kanis, 2018, Osteoporosis International.

FAM210A is a novel determinant of bone and muscle structure and strength

J. Richards, John A. Morris, S. Wing, 2018, Proceedings of the National Academy of Sciences.

Parathyroid hormone-related peptide and other mediators of skeletal manifestations of malignancy

R. Kremer, D. Goltzman, David Goltzman, 2020, Principles of Bone Biology.

Presentation of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop.

L. Mosekilde, M. Rubin, S. Silverberg, 2009, The Journal of clinical endocrinology and metabolism.

Malignancy-associated hypercalcemia: evaluation with a cytochemical bioassay for parathyroid hormone.

A. F. Stewart, A. Broadus, D. Goltzman, 1981, The Journal of clinical endocrinology and metabolism.

Medullary carcinoma of the human thyroid in monolayer culture. Morphological and cytochemical correlations

A. Tischler, D. Goltzman, H. Wolfe, 1977, Cancer.

Haploinsufficiency of parathyroid hormone-related peptide (PTHrP) results in abnormal postnatal bone development.

M. Lipman, N. Amizuka, A. Karaplis, 1996, Developmental biology.

Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death

B. Lanske, N. Amizuka, D. Goltzman, 1995, Molecular and cellular biology.

Purification of peptides with parathyroid hormone-like bioactivity from human and rat malignancies associated with hypercalcemia.

S. Rabbani, R. Kremer, D. Goltzman, 1986, Endocrinology.

Programmed cell death of chondrocytes and aberrant chondrogenesis in mice homozygous for parathyroid hormone-related peptide gene deletion.

N. Amizuka, D. Goltzman, A. Karaplis, 1996, Endocrinology.

Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation

N. Amizuka, D. Goltzman, A. Karaplis, 1994, The Journal of cell biology.

Management of corticosteroid-induced osteoporosis.

J. Sibley, G. Ioannidis, J. Adachi, 2000, Seminars in arthritis and rheumatism.

Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis

G. Abecasis, C. Greenwood, J. Richards, 2023, Nature Genetics.

Inferences from genetically modified mouse models on the skeletal actions of vitamin D

D. Goltzman, David Goltzman, D. Goltzman, 2015, The Journal of Steroid Biochemistry and Molecular Biology.

Structural requirements for the growth factor activity of the amino-terminal domain of urokinase.

A. Mazar, J. Henkin, S. Rabbani, 1992, The Journal of biological chemistry.

Influence of calcium and 1,25-dihydroxycholecalciferol on proliferation and proto-oncogene expression in primary cultures of bovine parathyroid cells.

G. Hendy, R. Kremer, D. Goltzman, 1989, Endocrinology.

Predicting fracture using 2D finite element modelling.

C. Kovacs, J. Adachi, R. Josse, 2012, Medical engineering & physics.

The effect of cyclooxygenase-2 inhibitors on bone mineral density: results from the Canadian Multicentre Osteoporosis Study

A. Tenenhouse, N. Kreiger, K. Schwartzman, 2006, Osteoporosis International.

Vitamin D and its receptor during late development.

John H. White, G. Hendy, D. Goltzman, 2015, Biochimica et biophysica acta.

Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus

R. Rizzoli, R. Eastell, L. Rejnmark, 2016, Osteoporosis International.

Reversal of hypercalcemia with the vitamin D analogue EB1089 in a human model of squamous cancer.

J. Rhim, S. Rabbani, R. Kremer, 1999, Cancer research.

The vitamin D analogue EB 1089 prevents skeletal metastasis and prolongs survival time in nude mice transplanted with human breast cancer cells.

L. Binderup, R. Kremer, D. Goltzman, 2000, Cancer research.

A Compilation of Partial Sequences of Randomly Selected cDNA Clones from the Rat Incisor

Y. Yamada, D. Goltzman, Y. Matsuki, 1995, Journal of dental research.

Vitamin D3 differentially regulates parathyroid hormone/parathyroid hormone-related peptide receptor expression in bone and cartilage.

N. Amizuka, D. Goltzman, J. White, 1999, The Journal of clinical investigation.

Urokinase overproduction results in increased skeletal metastasis by prostate cancer cells in vivo.

S. Rabbani, P. Brodt, D. Goltzman, 1994, Cancer research.

Antidepressant use and 10-year incident fracture risk: the population-based Canadian Multicentre Osteoporosis Study (CaMoS)

M. Abrahamowicz, W. Leslie, E. Rahme, 2014, Osteoporosis International.

Impact of Femoral Neck and Lumbar Spine BMD Discordances on FRAX Probabilities in Women: A Meta-analysis of International Cohorts

A. LaCroix, J. Kanis, J. Eisman, 2014, Calcified Tissue International.

Calcitonin receptors in the central nervous system of the rat.

D. Goltzman, A. Rizzo, David Goltzman, 1981, Endocrinology.

Abundant expression of parathyroid hormone-related protein in primary rat aortic smooth muscle cells accompanies serum-induced proliferation.

T. Clemens, J. Forrester, J. Fagin, 1991, The Journal of clinical investigation.

Regulation in vivo of the growth of Leydig cell tumors by antisense ribonucleic acid for parathyroid hormone-related peptide.

S. Rabbani, D. Goltzman, B. Liu, 1995, Endocrinology.

Enhanced growth of a human keratinocyte cell line induced by antisense RNA for parathyroid hormone-related peptide.

J. Rhim, R. Kremer, D. Goltzman, 1992, The Journal of biological chemistry.

Rat parathyroid hormone-like peptide: comparison with the human homologue and expression in malignant and normal tissue.

D. Banville, G. Hendy, S. Rabbani, 1989, Molecular endocrinology.

ras Activation of human prostate epithelial cells induces overexpression of parathyroid hormone-related peptide.

M. Webber, J. Rhim, N. Amizuka, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Recent studies on the biological action of parathyroid hormone (PTH)-related peptide (PTHrP) and PTH/PTHrP receptor in cartilage and bone.

John H. White, N. Amizuka, A. Karaplis, 2000, Histology and histopathology.

Effects of passive immunization against parathyroid hormone (PTH)-like peptide and PTH in hypercalcemic tumor-bearing rats and normocalcemic controls.

D. Goltzman, J. Henderson, P. D'amour, 1990, Endocrinology.

Dysregulation of parathyroid hormone-like peptide expression and secretion in a keratinocyte model of tumor progression.

J. Rhim, R. Kremer, M. Sebag, 1991, Cancer research.

Regulation of parathyroid hormone-like peptide in cultured normal human keratinocytes. Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion.

D. Banville, G. Hendy, W. Gulliver, 1991, The Journal of clinical investigation.

The biologic action of parathyroid hormone-related Peptide on bone and cartilage cells.

N. Amizuka, D. Goltzman, H. Ozawa, 1996, Tissue engineering.

SEQUENCES OF INTEREST: Gene-Encoding Parathyroid Hormone-Like Peptide: Nucleotide Sequence of the Rat Gene and Comparison with the Human Homologue

D. Banville, G. Hendy, D. Goltzman, 1990 .

Parathyroid hormone-like peptide: Molecular characterization and biological properties

D. Banville, G. Hendy, D. Goltzman, 1989, Trends in Endocrinology & Metabolism.

Regulation of parathyroid hormone-related peptide by estradiol: effect on tumor growth and metastasis in vitro and in vivo.

G. Chen, S. Rabbani, D. Goltzman, 2005, Endocrinology.

Biosynthesis and processing of endogenous parathyroid hormone related peptide (PTHRP) by rat Leydig cell tumor H-500.

S. Rabbani, D. Goltzman, M. Haq, 1993, Biochemistry.

Parathyroid-hormone-related peptide in hematologic malignancies.

R. Kremer, D. Goltzman, V. Papavasiliou, 1996, The American journal of medicine.

Influence of the amino-terminus on in vitro and in vivo biological activity of synthetic parathyroid hormone-like peptides of malignancy.

G. Hendy, S. Rabbani, D. Goltzman, 1988, Endocrinology.

Parathyroid hormone-related peptide and hypercalcemia of malignancy.

D. Goltzman, J. Henderson, David Goltzman, 1997, Cancer treatment and research.

Studies of the multiple molecular forms of bioactive parathyroid hormone and parathyroid hormone-like substances.

M. Koutsilieris, S. Rabbani, D. Goltzman, 1986, Recent progress in hormone research.

Characterization of the human parathyroid hormone-like peptide gene. Functional and evolutionary aspects.

David Goltzman, G. N. Hendy, Denis Banville, 1989, The Journal of biological chemistry.

Increased PTHRP production by a tyrosine kinase oncogene, Tpr-Met: role of the Ras signaling pathway.

Morag Park, S. Rabbani, D. Goltzman, 1996, The American journal of physiology.

Antisense-mediated inhibition of parathyroid hormone-related peptide production in a keratinocyte cell line impedes differentiation.

J. Rhim, R. Kremer, M. Sebag, 1994, Molecular endocrinology.

Gene for parathyroid hormone-like peptide is on rat chromosome 2.

D. Banville, G. Hendy, M. Yoshida, 1988, Biochemical and biophysical research communications.

Tissue-specific targeting of the pthrp gene: the generation of mice with floxed alleles.

D. Goltzman, A. Karaplis, M. Pollak, 2001, Endocrinology.

Expression and regulation of parathyroid hormone-related peptide in normal and malignant melanocytes.

R. Kremer, D. Goltzman, V. Papavasiliou, 2000, American journal of physiology. Cell physiology.

An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells.

A. Mazar, J. Henkin, D. Banville, 1990, Biochemical and biophysical research communications.

A vitamin D analogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo.

S. Rabbani, R. Kremer, D. Goltzman, 1993, The Journal of clinical investigation.