Udit Sheth

Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins

Shu Liu, L. Petrucelli, J. Rothstein, 2022, Science Translational Medicine.

High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation

Peter K. Todd, M. Ivanova, Michael G Kearse, 2019, The Journal of Biological Chemistry.

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

M. Mattson, Y. Pang, Na Zhao, 2021, Nature Neuroscience.

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

M. Mattson, Liewei Wang, D. Dickson, 2021, bioRxiv.

Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo

T. Arzberger, J. Herms, A. Schepers, 2023, Acta Neuropathologica Communications.

Fluid biomarkers for amyotrophic lateral sclerosis: a review

T. Gendron, Udit Sheth, Katherine E Irwin, 2024, Molecular neurodegeneration.

Aberrant splicing exonizes C9ORF72 repeat expansion in ALS/FTD

T. Gendron, Denethi Wijegunawardana, Suzhou Yang, 2023, bioRxiv.