Masaki Ima

Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.

T. Nakao, M. Fujita, T. Nabe, 2015, Journal of medicinal chemistry.

Discovery of Highly Potent Dual CysLT1 and CysLT2 Antagonist.

M. Fujita, Y. Nakayama, Shinya Takahashi, 2014, ACS medicinal chemistry letters.

Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists.

M. Toda, T. Matsui, Shingo Yamamoto, 2006, Bioorganic & medicinal chemistry.

Further optimization of sulfonamide analogs as EP1 receptor antagonists: synthesis and evaluation of bioisosteres for the carboxylic acid group.

M. Toda, T. Matsui, S. Ohuchida, 2006, Bioorganic & medicinal chemistry.

Enantioselective Synthesis of Lythraceae Alkaloid Lasubine II via Optically Active 2-Isoxazoline.

Y. Ukaji, K. Inomata, Masaki Ima, 2000 .

Discovery of a potent, orally available dual CysLT₁ and CysLT₂ antagonist with dicarboxylic acid.

M. Fujita, Y. Nakayama, Shinya Takahashi, 2015, Bioorganic & medicinal chemistry.

Discovery of heteroaryl sulfonamides as new EP1 receptor selective antagonists.

M. Toda, T. Matsui, Shingo Yamamoto, 2006, Bioorganic & medicinal chemistry.