G. Horne

发表

(6S)-Methyl-l-swainsonine [(1R,2S,6S,8S,8aS)-6-methyloctahydroindolizine-1,2,8-triol]

D. Watkin, G. Fleet, A. Håkansson, 2007 .

Methyl 3,6-anhydro-4-azido-5,7-O-(S)-benzylidene-2,4-dideoxy-d-talo-heptonate

G. Fleet, R. Nash, R. Cooper, 2004 .

Hydroxylated C-branched pyrrolidines, C-branched prolines and C-branched piperidines from a 2-C-methyl sugar lactone; efficient azide displacement of a tertiary triflate with inversion of configuration

G. Fleet, F. P. Cruz, G. Horne, 2008 .

Carbon-branched carbohydrate chirons: synthesis of C-3 and C-4-branched sugar lactones derived from d-erythronolactone

G. Fleet, S. F. Jenkinson, K. V. Booth, 2009 .

Synthesis of eight stereoisomers of pochonicine: nanomolar inhibition of β-N-acetylhexosaminidases.

T. Nitoda, G. Fleet, Jian-She Zhu, 2013, The Journal of organic chemistry.

Iminosugars past, present and future: medicines for tomorrow.

D. H. Williams, F. Wilson, R. Storer, 2011, Drug discovery today.

Synthesis of fully substituted polyhydroxylated pyrrolizidines via Cope-House cyclization.

Wei Zhang, G. Fleet, A. Kato, 2011, Organic letters.

Synthesis of the naringinase inhibitors l-swainsonine and related 6-C-methyl-l-swainsonine analogues: (6R)-C-methyl-l-swainsonine is a more potent inhibitor of l-rhamnosidase by an order of magnitude than l-swainsonine

G. Besra, M. Wormald, S. Gurcha, 2008 .

Looking glass inhibitors: synthesis of a potent naringinase inhibitor l-DIM [1,4-dideoxy-1,4-imino-l-mannitol], the enantiomer of DIM [1,4-dideoxy-1,4-imino-d-mannitol] a potent α-d-mannosidase inhibitor

G. Fleet, A. Kato, A. Håkansson, 2007 .

Iminosugars: Therapeutic Applications and Synthetic Considerations

G. Horne, 2014 .

Total synthesis of nucleobase-modified adenophostin A mimics.

S. Shuto, B. Potter, G. Horne, 2001, Chemistry.

Isolation synthesis and glycosidase inhibition profile of 3-epi-casuarine

R. Dwek, M. Wormald, G. Fleet, 2006 .

Therapeutic applications of iminosugars: current perspectives and future opportunities.

F. Wilson, G. Horne, 2011, Progress in medicinal chemistry.

Steviamine, a new indolizidine alkaloid from Stevia Rebaudiana

A. Michalik, G. Fleet, A. Kato, 2010 .

General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.

K. Izumori, G. Fleet, S. Nakagawa, 2013, The Journal of organic chemistry.

Preparation of glycosyl fluorides from phenyl 1-seleno- and phenyl 1-telluroglycosides

W. Mackie, G. Horne, 1999 .

Structural determinants of adenophostin A activity at inositol trisphosphate receptors.

A. M. Riley, S. Shuto, C. Taylor, 2001, Molecular pharmacology.

Total Synthesis of Nucleobase‐Modified Adenophostin A Mimics.

S. Shuto, B. Potter, G. Horne, 2002 .

D-6-Deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, a mimic of d-myo-inositol 1,3,4,5-tetrakisphosphate: biological activity and pH-dependent conformational properties.

R. Penner, A. Fleig, M. Hirata, 2004, Biochemical and biophysical research communications.

First derivatives of myo-inositol 1,4,6-trisphosphate modified at positions 2 and 3: structural analogues of D-myo-inositol 1,4,5-trisphosphate.

B. Potter, S. J. Mills, G. Horne, 2004, Carbohydrate research.

Synthesis of the enantiomers of 6-deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, structural analogues of myo-inositol 1,3,4,5-tetrakisphosphate.

B. Potter, G. Horne, 2001, Chemistry.