S. Hoerer

发表

Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo.

P. Nicklin, G. Roth, M. Ferrara, 2017, ACS medicinal chemistry letters.

Screening for soluble expression constructs using cell-free protein synthesis.

T. Lamla, S. Hoerer, M. Bauer, 2006, International journal of biological macromolecules.

Boosting antibody developability through rational sequence optimization

Daniel Seeliger, Patrick Garidel, Michaela Blech, 2015, mAbs.

Crystal structure of the human liver X receptor beta ligand-binding domain in complex with a synthetic agonist.

H. Nar, A. Heckel, Stefan Hoerer, 2004, Journal of molecular biology.

Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter

H. Nar, Zhixin Chen, Lei Chen, 2021, Nature.

Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule.

N. Vaidehi, C. Tautermann, S. Hobson, 2018, Journal of medicinal chemistry.

Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter

H. Nar, Zhixin Chen, Lei Chen, 2021, Nature.

Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor β receptor I (TGFβRI).

D. Mennerich, A. Schnapp, G. Roth, 2010, Journal of medicinal chemistry.

Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators.

M. Garneau, S. Hobson, P. Sieger, 2018, Bioorganic & medicinal chemistry.

Solution structure and synaptic analyses reveal molecular mechanisms of bispecific T cell engagers

D. Klenerman, H. Nar, Edward Jenkins, 2023, bioRxiv.