J. Sisler

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Small airway epithelial cells exposure to printer-emitted engineered nanoparticles induces cellular effects on human microvascular endothelial cells in an alveolar-capillary co-culture model

V. Castranova, Sherri A. Friend, D. Schwegler-Berry, 2015, Nanotoxicology.

Dear Granger: I appreciate the opportunity to submit a revised manuscript to Cell Metabolism entitled: “Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity”. We have modified the manuscript to include most of the experiments the reviewers suggested. Below

K. Rajewsky, P. Seale, T. Harris, 2022 .

Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production

P. Shaw, H. Baumann, K. Takabe, 2017, Science Signaling.

Toxicological assessment of dust from sanding micronized copper-treated lumber in vivo.

W. McKinney, V. Castranova, D. Porter, 2019, Journal of hazardous materials.

Title Differential pulmonary effects of CoO and La 2 O 3 metal oxide nanoparticle responses during aerosolized inhalation in mice Permalink

T. Xia, A. Nel, W. McKinney, 2016 .

Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727*

P. Dent, K. Valerie, A. Yacoub, 2013, The Journal of Biological Chemistry.

Toxicological Assessment of CoO and La2O3 Metal Oxide Nanoparticles in Human Small Airway Epithelial Cells.

V. Castranova, Michael E. Andrew, D. Schwegler-Berry, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

The Role of Tyk2 in Regulating Energy Expenditure and Preventing Obesity

C. Croniger, Marta Derecka, A. Larner, 2012 .

The Fate of Inhaled Nanoparticles: Detection and Measurement by Enhanced Dark-field Microscopy

Liying Wang, V. Castranova, D. Porter, 2018, Toxicologic pathology.

Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice

T. Xia, A. Nel, W. McKinney, 2015, Particle and Fibre Toxicology.

Mouse pulmonary response to dust from sawing Corian®, a solid-surface composite material

R. Mercer, L. Battelli, Sherri A. Friend, 2019, Journal of toxicology and environmental health. Part A.

Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice

Yong Qian, Vincent Castranova, Tian Xia, 2015, Particle and Fibre Toxicology.

Assessment of reactive oxygen species generated by electronic cigarettes using acellular and cellular approaches.

S. Leonard, P. Demokritou, D. Bello, 2018, Journal of hazardous materials.

In vitro toxicological evaluation of surgical smoke from human tissue

Yong Qian, Martin Harper, Ryan F. LeBouf, 2018, Journal of Occupational Medicine and Toxicology.

Effects of intratracheally instilled laser printer-emitted engineered nanoparticles in a mouse model: A case study of toxicological implications from nanomaterials released during consumer use.

X. Lu, I. Koturbash, V. Castranova, 2016, NanoImpact.

A 21-day sub-acute, whole-body inhalation exposure to printer-emitted engineered nanoparticles in rats: Exploring pulmonary and systemic effects

V. Castranova, C. Christophi, J. Godleski, 2019, NanoImpact.

The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes

T. Harris, C. Croniger, Marta Derecka, 2015, PloS one.

Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity.

A. Russell, K. Rajewsky, P. Seale, 2012, Cell metabolism.

Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled carbon nanotubes on human small airway epithelial cells.

M. Terrones, W. Ding, V. Castranova, 2015, Toxicology.

Assessment of reactive oxygen species generated by electronic cigarettes using acellular and cellular approaches.

S. Leonard, P. Demokritou, D. Bello, 2018, Journal of hazardous materials.

The Fate of Inhaled Nanoparticles: Detection and Measurement by Enhanced Dark-field Microscopy

Liying Wang, V. Castranova, D. Porter, 2018, Toxicologic pathology.

Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production

P. Shaw, H. Baumann, K. Takabe, 2017, Science Signaling.

247 : Stat1 inhibits mitochondrial biogenesis

Marta Derecka, E. Lesnefsky, A. Larner, 2013 .

Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells

T. Harris, Marta Derecka, B. Strobl, 2016, Endocrinology.