H. Brachwitz

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Analogs of alkyllysophospholipids: chemistry, effects on the molecular level and their consequences for normal and malignant cells.

H. Brachwitz, C. Vollgraf, 1995, Pharmacology & therapeutics.

Halo lipids, 8. Synthesis of O-alkyl-O-alkyl-O-(2,2,2-trifluoroethyl)glycerols and O-alkyl-O-(2,2,2-trifluoroethyl)glycero-phosphocholines☆

P. Franke, P. Langen, R. Hintsche, 1984 .

Alteration of DNA topoisomerase II activity during infection of H9 cells by human immunodeficiency virus type 1 in vitro: a target for potential therapeutic agents.

W. Müller, P. Langen, A. Maidhof, 1990, Antiviral research.

Opposite effects on cytosolic Ca2+ of antitumor phospholipids by induction of calcium influx and activation of endoplasmic reticulum Ca(2+)-ATPase.

P. Langen, H. Brachwitz, J. Bergmann, 1998, Cell calcium.

New nucleoside-5'-alkylphosphonophosphates and related compounds containing 2'-deoxycytidine, thymidine and adenosine as nucleoside component. Syntheses and their effects on tumor cell growth in vitro.

W. Berdel, P. Langen, H. Brachwitz, 1997, Chemistry and Physics of Lipids.

Synthesis and antiproliferative activity of cytidine-5'-alkylphosphonophosphates and structurally related compounds.

W. Berdel, P. Langen, U. Lachmann, 1996, Chemistry and physics of lipids.

1-beta-D-Arabinofuranosylcytosine-5'-alkylphosphonophosphates and diphosphates: new orally active derivatives of ara-C.

W. Berdel, P. Langen, I. Fichtner, 1998, Journal of lipid research.

1-bD-Arabinofuranosylcytosine-5 9-alkylphosphonophosphates and diphosphates : new orally active derivatives of araC

W. Berdel, P. Langen, I. Fichtner, 1997 .

Hydroximsäurederivate. IV. 3‐Acyl‐1,2,4‐oxadiazole aus N‐Acyl‐ und N‐Äthoxycarbonyl‐α‐amino‐ketonen

H. Brachwitz, 1971 .

Cellular signalling as a target in cancer chemotherapy. Phospholipid analogues as inhibitors of mitogenic signal transduction.

H. Grunicke, K. Maly, F. Uberall, 1996, Advances in enzyme regulation.

Halo lipids. 10. Synthesis and cytostatic activity of O-alkylglycerophospho-L-serine analogs.

A. Hermetter, P. Langen, F. Paltauf, 1990, Chemistry and physics of lipids.

Halo lipids. V. Synthesis, nuclear magnetic resonance spectra and cytostatic properties of halo analogues of alkyllysophospholipids.

P. Langen, R. Hintsche, H. Brachwitz, 1982, Chemistry and physics of lipids.

Multiple effects of antitumor alkyl-lysophospholipid analogs on the cytosolic free Ca2+ concentration in a normal and a breast cancer cell line.

P. Langen, I. Junghahn, H. Brachwitz, 1994, Anticancer research.

Alkylphospho-L-serine analogues: Synthesis of cytostatically active alkylphosphono derivatives

P. Langen, H. Brachwitz, J. Bergmann, 1997 .

Modulation of the cytosolic Ca++ concentration by alkylphospho-L-serine analogs: relation to their antiproliferative action.

P. Langen, I. Junghahn, H. Brachwitz, 1997, Journal of lipid mediators and cell signalling.

Alkylphospho-L-serine Analogues: Synthesis of Cytostatically Active Alkylphosphono Derivatives.

M. Oelke, P. Langen, H. Brachwitz, 1997 .

Effect of ALP analogs on inositol trisphosphate formation in H184 mammary epithelial cells before and after transfection with v-erb B oncogene.

P. Langen, I. Junghahn, H. Brachwitz, 1995, Anticancer research.

Cytostatic effects of various alkyl phospholipid analogues on different cells in vitro.

P. Langen, K. Eckert, H. Maurer, 1992, Anticancer research.

Hydroximsäurederivate. VI. 1,2,4-Oxadiazole aus N-Acylamino-acetonitrilen

H. Brachwitz, 1972 .

Inhibition of proliferation of Ehrlich ascites carcinoma cells in vitro and in vivo by halogeno analogues of long chain acyl- and alkylglycerols.

P. Langen, H. Brachwitz, J. Schildt, 1979, Acta biologica et medica Germanica.

Cytostatic activity of synthetic O-alkylglycerolipids.

P. Langen, D. Arndt, I. Fichtner, 1987, Lipids.

Synthesis and antiproliferative potency of 9-beta-D-arabinofuranosyl-2-fluoroadenine phospholipid adducts.

P. Langen, H. Brachwitz, J. Bergmann, 1999, Bioorganic & medicinal chemistry.

Interference of new alkylphospholipid analogues with mitogenic signal transduction

H. Grunicke, F. Überall, K. Maly, 1995, Journal of Cancer Research and Clinical Oncology.