Brian M. Lacey

发表

Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds.

X. Fradera, Haiyan Xu, M. Bittinger, 2021, ACS medicinal chemistry letters.

of MC-1, a Novel Siderophore-Conjugated Monocarbam 2

L. Aschenbrenner, C. McPherson, A. Tomaras, 2012 .

Selenium in thioredoxin reductase: a mechanistic perspective.

R. Hondal, S. Flemer, B. Eckenroth, 2008, Biochemistry.

Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5).

M. Altman, Haiyan Xu, P. Siliphaivanh, 2020, ACS medicinal chemistry letters.

Investigation of the C-terminal redox center of high-Mr thioredoxin reductase by protein engineering and semisynthesis.

R. Hondal, B. Eckenroth, A. Lothrop, 2007, Biochemistry.

Early Insights into the Interactions of Different β-Lactam Antibiotics and β-Lactamase Inhibitors against Soluble Forms of Acinetobacter baumannii PBP1a and Acinetobacter sp. PBP3

L. Rice, V. Shanmugasundaram, R. Bonomo, 2012, Antimicrobial Agents and Chemotherapy.

Distinctive attributes of β-lactam target proteins in Acinetobacter baumannii relevant to development of new antibiotics.

V. Shanmugasundaram, K. Geoghegan, Xidong Feng, 2011, Journal of the American Chemical Society.

Pharmacological inhibition of hematopoietic progenitor kinase 1 positively regulates T-cell function

Haiyan Xu, M. Bittinger, J. Methot, 2020, PloS one.

Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.

Andrew M Haidle, Matthew L. Maddess, J. Cumming, 2022, Journal of medicinal chemistry.

An orally available non-nucleotide STING agonist with antitumor activity

Andrew M Haidle, J. Cumming, I. Kariv, 2020, Science.

Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa

J Richard Miller, Veerabahu Shanmugasundaram, V. Shanmugasundaram, 2010, Proceedings of the National Academy of Sciences.

INVESTIGATION INTO THE ROLE OF THE C-TERMINAL VICINAL CYSTEINE RESIDUES IN HIGH Mr THIOREDOXIN REDUCTASES

Brian M. Lacey, 2008 .

INVESTIGATION INTO THE ROLE OF THE C-TERMINAL VICINAL CYSTEINE RESIDUES IN HIGH Mr THIOREDOXIN

Brian M. Lacey, 2008 .

Characterization of mitochondrial thioredoxin reductase from C. elegans.

R. Hondal, Brian M. Lacey, 2006, Biochemical and biophysical research communications.

Clinically Relevant Gram-Negative Resistance Mechanisms Have No Effect on the Efficacy of MC-1, a Novel Siderophore-Conjugated Monocarbam

L. Aschenbrenner, C. McPherson, M. Lemmon, 2012, Antimicrobial Agents and Chemotherapy.

Driving Drug Discovery with Biophysical Information

G. Karam, V. Shanmugasundaram, A. Palmer, 2017 .

Development of High-Throughput Assays for Evaluation of Hematopoietic Progenitor Kinase 1 Inhibitors

I. Kariv, X. Chai, X. Fradera, 2020, SLAS discovery : advancing life sciences R & D.

The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.

Ryan V. Quiroz, Daniel S Spellman, Haiyan Xu, 2021, Journal of medicinal chemistry.

Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING.

M. Altman, H. Hatch, B. Pan, 2018, ACS medicinal chemistry letters.

Identification of Potent Reverse Indazole Inhibitors for HPK1.

X. Fradera, Haiyan Xu, M. Bittinger, 2021, ACS medicinal chemistry letters.

Synthesis of peptide substrates for mammalian thioredoxin reductase

R. Hondal, Brian M. Lacey, Stevenson Flemer Jr, 2008, Journal of peptide science : an official publication of the European Peptide Society.

Early Insights into the Interactions of Different β-Lactam Antibiotics and β-Lactamase Inhibitors against Soluble Forms of Acinetobacter baumannii PBP1a and Acinetobacter sp. PBP3

L. Rice, V. Shanmugasundaram, R. Bonomo, 2012, Antimicrobial Agents and Chemotherapy.

Early Insights into the Interactions of Different (cid:1) -Lactam Antibiotics and (cid:1) -Lactamase Inhibitors against Soluble Forms of Acinetobacter baumannii PBP1a and Acinetobacter sp. PBP3

V. Shanmugasundaram, J. Buynak, Marion J. Skalweit, 2012 .

Multiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-coil Domain Truncations.

J. O'neil, Xiaohong Zhu, M. Demma, 2020, The Journal of organic chemistry.