R. Liskamp

发表

A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group

T. Vermonden, W. Hennink, C. Rijcken, 2022, Bioconjugate chemistry.

Design, Development and Clinical Translation of CriPec®-based Core-Crosslinked Polymeric Micelles.

W. Hennink, R. Mathijssen, T. Lammers, 2022, Advanced drug delivery reviews.

Orthogonal Covalent Entrapment of Cargo into Biodegradable Polymeric Micelles via Native Chemical Ligation

T. Vermonden, W. Hennink, Erik R Hebels, 2022, Biomacromolecules.

Synthesis of tris-tertiary amine CycloTriVeratrilene (TACTV) derivatives as water soluble pre-organized three aromatic ring containing molecular scaffolds for the construction of protein mimics

Susan Gannon, D. Ward, H. van de Langemheen, 2019, Tetrahedron Letters.

A conformationally constrained fused tricyclic nisin AB-ring system mimic toward an improved pyrophosphate binder of lipid II

E. Breukink, D. Rijkers, J. Kemmink, 2014 .

Synthesis of pyrazole containing α-amino acids via a highly regioselective condensation/aza-Michael reaction of β-aryl α,β-unsaturated ketones.

A. Sutherland, R. Artschwager, Lynne Gilfillan, 2015, Organic & biomolecular chemistry.

Synthesis of peptides containing a sulfinamide or a sulfonamide transition-state isostere

G. A. Marel, W. J. Moree, R. Liskamp, 1993 .

Synthesis of peptides containing the β-substituted aminoethane sulfinamide or sulfonamide transition-state isostere derived from amino acids

G. A. Marel, W. J. Moree, R. Liskamp, 1992 .

Peptides containing a sulfinamide or a sulfonamide moiety: New transition-state analogues

G. A. Marel, W. J. Moree, R. Liskamp, 1991 .

2.2 CuAAC in Peptidomimetics and Protein Mimics

R. Liskamp, T. J. Meuleman, 2022, Click Chemistry.

Synthesis of bicyclic tripeptides inspired by the ABC-ring system of vancomycin through ruthenium-based cyclization chemistries

D. Rijkers, J. Kemmink, Xin Yang, 2017 .

Peptides Containing the Novel Methylphosphinamide Transition‐State Isostere.

J. H. Boom, G. A. Marel, W. J. Moree, 1994 .

Synthesis of Peptides Containing the β‐Substituted Aminoethane Sulfinamide or Sulfonamide Transition‐State Isostere Derived from Amino Acids.

G. A. Marel, W. J. Moree, R. Liskamp, 1993 .

Synthesis of Peptidosulfinamides and Peptidosulfonamides: Peptidomimetics Containing the Sulfinamide or Sulfonamide Transition-State Isostere

G. A. Marel, W. J. Moree, R. Liskamp, 1995 .

Expedient synthesis of a novel asymmetric selectively deprotectable derivative of the ATAC scaffold

A. J. Brouwer, R. Liskamp, H. Langemheen, 2014 .

Design and Synthesis of HCV-E2 Glycoprotein Epitope Mimics in Molecular Construction of Potential Synthetic Vaccines

Arvind H. Patel, V. Cowton, Vanessa M. Cowton, 2021, Viruses.

An orthogonally protected CycloTriVeratrylene (CTV) as a highly pre-organized molecular scaffold for subsequent ligation of different cyclic peptides towards protein mimics.

H. van de Langemheen, R. Liskamp, Ondřej Longin, 2017, Bioorganic & medicinal chemistry.

Polar Hinges as Functionalized Conformational Constraints in (Bi)cyclic Peptides

Claire Wilson, C. Heinis, J. Bijl, 2017, Chembiochem : a European journal of chemical biology.

Improving the aqueous solubility of HCV‐E2 glycoprotein epitope mimics by cyclization using POLAR hinges

Arvind H. Patel, Vanessa M. Cowton, R. Liskamp, 2020, Journal of peptide science : an official publication of the European Peptide Society.

Synthetic antibody protein mimics of infliximab by molecular scaffolding on novel CycloTriVeratrilene (CTV) derivatives.

M. Hezwani, H. van de Langemheen, R. Liskamp, 2018, Organic & biomolecular chemistry.

Synthesis of Peptidosulfinamides and Peptidosulfonamides: Peptidomimetics Containing the Sulfinamide or Sulfonamide Transition- State Isostere.

G. A. Marel, W. J. Moree, R. Liskamp, 1995 .

Molecular Construction of Sulfonamide Antisense Oligonucleotides.

G. Burley, L. Reichenbach, R. Liskamp, 2019, The Journal of organic chemistry.

A new perspective on fungal metabolites: identification of bioactive compounds from fungi using zebrafish embryogenesis as read-out

A. Heck, J. den Hertog, T. Boekhout, 2019, Scientific Reports.

Glucocorticoid-loaded core-cross-linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis.

C. van Nostrum, W. Hennink, R. Schiffelers, 2012, Angewandte Chemie.

Tailoring Polyethers for Post-polymerization Functionalization by Cross Metathesis.

J. Prunet, Stephen Morrison, R. Liskamp, 2018, Organic Letters.

Highly tunable thiosulfonates as a novel class of cysteine protease inhibitors with anti-parasitic activity against Schistosoma mansoni.

A. Kreidenweiss, R. J. Liskamp, E. Koehne, 2019, Bioorganic & medicinal chemistry.

TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide–alkyne cycloaddition reactions†

M. Honing, H. Ippel, T. Meulemans, 2020, Chemical science.

Solid-phase synthesis of O-phosphorothioylserine- and -threonine-containing peptides as well as of O-phosphoserine- and -threonine-containing peptides

J. H. Boom, W. J. Moree, D. B. Bont, 1993 .

Highly potent antimicrobial peptide derivatives of bovine cateslytin

T. M. Postma, R. J. Liskamp, R. Liskamp, 2016 .

Azide-alkyne cycloaddition affording enzymatically tunable bisubstrate based inhibitors of histone acetyltransferase PCAF.

R. Liskamp, J. van Ameijde, R. Ruijtenbeek, 2014, Bioorganic & medicinal chemistry letters.

TAC-scaffolded tripeptides as artificial hydrolytic receptors: a combinatorial approach toward esterase mimics.

R. Liskamp, H. B. Albada, R. Liskamp, 2008, Journal of combinatorial chemistry.

A selectively deprotectable triazacyclophane scaffold for the construction of artificial receptors.

R. Liskamp, T. Opatz, R. Liskamp, 2001, Organic letters.

Synthesis of a tricyclic hexapeptide -via two consecutive ruthenium-catalyzed macrocyclization steps- with a constrained topology to mimic vancomycin's binding properties toward D-Ala-D-Ala dipeptide.

D. Rijkers, J. Kemmink, Xin Yang, 2022, Bioorganic & medicinal chemistry letters.

Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00113h

T. M. Postma, M. Riehle, Ezequiel Silva Nigenda, 2018, MedChemComm.