Mahmoud F. Abo-Ashour

发表

Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity

H. Abdel‐Aziz, T. Al-Warhi, Wagdy M. Eldehna, 2022, Scientific Reports.

Development of isatin-thiazolo[3,2-a]benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and molecular dynamics investigations.

H. Abdel‐Aziz, T. Al-Warhi, Wagdy M. Eldehna, 2021, Bioorganic chemistry.

Synthesis and biological evaluation of 2-aminothiazole-thiazolidinone conjugates as potential antitubercular agents.

Riham F. George, Wagdy M. Eldehna, S. M. Abou-Seri, 2018, Future medicinal chemistry.

Novel indole-thiazolidinone conjugates: Design, synthesis and whole-cell phenotypic evaluation as a novel class of antimicrobial agents.

Riham F. George, S. Bhakta, Wagdy M. Eldehna, 2018, European journal of medicinal chemistry.

3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies.

C. Supuran, M. M. Al-Sanea, H. Abdel‐Aziz, 2020, European journal of medicinal chemistry.

Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies

M. M. Al-Sanea, H. Abdel‐Aziz, T. Al-Warhi, 2020, Journal of enzyme inhibition and medicinal chemistry.

Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation

Wagdy M. Eldehna, Hany S. Ibrahim, M. Elaasser, 2018, Journal of enzyme inhibition and medicinal chemistry.

Identification of N-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities.

C. Supuran, M. Abdelgawad, M. M. Al-Sanea, 2021, European journal of medicinal chemistry.

Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies.

C. Supuran, H. Abdel‐Aziz, Wagdy M. Eldehna, 2019, Bioorganic chemistry.

SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX.

C. Supuran, D. Vullo, Ghada S. Hassan, 2019, Bioorganic chemistry.

3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights.

C. Supuran, V. Kryštof, Wagdy M. Eldehna, 2019, European journal of medicinal chemistry.

Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents.

C. Supuran, Ghada S. Hassan, H. Abdel‐Aziz, 2019, European journal of medicinal chemistry.

Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment

C. Supuran, H. Abdel‐Aziz, T. Al-Warhi, 2022, Journal of enzyme inhibition and medicinal chemistry.

Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail/dual tail approaches: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies.

C. Supuran, A. Angeli, H. Abdel‐Aziz, 2021, European journal of medicinal chemistry.

Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies.

C. Supuran, Mohamed Fares, H. Abdel‐Aziz, 2017, European journal of medicinal chemistry.

Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells

R. Ahmad, H. Abdel‐Aziz, T. Al-Warhi, 2020, Journal of enzyme inhibition and medicinal chemistry.

Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies.

C. Supuran, Wagdy M. Eldehna, S. M. Abou-Seri, 2018, European journal of medicinal chemistry.

Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and molecular modeling studies.

H. Abdel‐Aziz, S. M. Abou-Seri, Mohammed E. Abo-El Fetoh, 2023, Bioorganic chemistry.

Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity

H. Abdel‐Aziz, T. Al-Warhi, Wagdy M. Eldehna, 2022, Scientific Reports.

Novel anti-inflammatory agents featuring phenoxy acetic acid moiety as a pharmacophore for selective COX-2 inhibitors: Synthesis, biological evaluation, histopathological examination and molecular modeling investigation.

S. M. Abou-Seri, Mahmoud A. El Hassab, Mohammed E. Abo-El Fetoh, 2024, Bioorganic chemistry.