Jiaqi Zhou

发表

Exploration of novel phthalazinone derivatives as potential efflux transporter inhibitors for reversing multidrug resistance and improving the oral absorption of paclitaxel.

Wen-long Huang, Hai Qian, Ziyu Yin, 2022, European journal of medicinal chemistry.

Synthesis and anti-cancer evaluation of folic acid-peptide- paclitaxel conjugates for addressing drug resistance.

Wen-long Huang, Hai Qian, Ying Zhu, 2019, European journal of medicinal chemistry.

Novel lipid side chain modified exenatide analogs emerged prolonged glucoregulatory activity and potential body weight management properties.

Wen-long Huang, Hai Qian, Z. Hou, 2019, Bioorganic & medicinal chemistry.

Structure-based discovery of receptor tyrosine kinase AXL degraders with excellent anti-tumor activity by selectively degrading AXL and inducing methuosis.

Wen-long Huang, Hai Qian, Huiting Jia, 2022, European journal of medicinal chemistry.

Synthesis and biological evaluation of JL-A7 derivatives as potent ABCB1 inhibitors.

Wen-long Huang, Hai Qian, Haiyan Lin, 2017, Bioorganic & medicinal chemistry.

Novel benzodiazepines derivatives as analgesic modulating for Transient receptor potential vanilloid 1.

Hai Qian, Qifei Li, Chunxiao Liu, 2018, Bioorganic & medicinal chemistry.

Phenylquinoline transient receptor potential vanilloid 1 antagonists for the treatment of pain: Discovery of 1-(2-phenylquinoline-4-carbonyl)-N-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide.

Wen-long Huang, Hai Qian, Huilan Li, 2017, Bioorganic & medicinal chemistry.

Designed P-glycoprotein inhibitors with triazol-tetrahydroisoquinoline-core increase doxorubicin-induced mortality in multidrug resistant K562/A02 cells.

Wen-long Huang, Hai Qian, Cheng Jiang, 2019, Bioorganic & medicinal chemistry.

Development of cell-permeable peptide-based PROTACs targeting estrogen receptor α.

Wen-long Huang, Hai Qian, Qifei Li, 2019, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of N-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide derivatives as novel P-glycoprotein inhibitors reversing multidrug resistance.

Hai Qian, W. Shi, Qianqian Qiu, 2019, Bioorganic chemistry.

Exploration of novel anti-angiogenic PEDF-derived peptides with improved activitives by inhibiting proliferation, suppressing migration, and inducing 67LR internalization.

Hai Qian, W. Shi, Haiyan Lin, 2021, Bioorganic chemistry.

A designed cyclic peptide based on Trastuzumab used to construct peptide-drug conjugates for its HER2-targeting ability.

Wen-long Huang, Hai Qian, W. Shi, 2021, Bioorganic chemistry (Print).

Source and exploration of the peptides used to construct peptide-drug conjugates.

Wen-long Huang, Hai Qian, W. Shi, 2021, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel FFA1/GPR40 agonists: New breakthrough in an old scaffold.

Wen-long Huang, Hai Qian, Chunxiao Liu, 2019, European journal of medicinal chemistry.

Design, synthesis and bioactivity evaluation of novel fusion peptides and their CPT conjugates inducing effective anti-tumor responses on HER2 positive tumors.

Jiaqi Zhou, Zhancheng Xie, Jialing Wang, 2023, European journal of medicinal chemistry.