Michelle S. Pearson

发表

Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy

L. Koetzner, Gary Lee, Y. Rotshteyn, 2005, Neuropharmacology.

Pharmacological characterisation of a rat model of incisional pain

K. Walker, G. Whiteside, L. Mark, 2004, British journal of pharmacology.

Pharmacological Characterization of the Novel and Selective α7 Nicotinic Acetylcholine Receptor–Positive Allosteric Modulator BNC375

J. Uslaner, F. Thomson, A. Harvey, 2020, The Journal of Pharmacology and Experimental Therapeutics.

A role for cannabinoid receptors, but not endogenous opioids, in the antinociceptive activity of the CB2-selective agonist, GW405833.

K. Valenzano, G. Whiteside, L. Mark, 2005, European journal of pharmacology.

DiPOA ([8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic Acid), a Novel, Systemically Available, and Peripherally Restricted Mu Opioid Agonist with Antihyperalgesic Activity: II. In Vivo Pharmacological Characterization in the Rat

J. Pomonis, Y. Rotshteyn, K. Walker, 2004, Journal of Pharmacology and Experimental Therapeutics.

DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted Mu opioid agonist with antihyperalgesic activity: II. In vivo pharmacological characterization in the rat.

M. Fundytus, J. Pomonis, Y. Rotshteyn, 2004, The Journal of pharmacology and experimental therapeutics.

Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation

Craig W. Lindsley, William J. Ray, Michelle Pearson, 2009, Proceedings of the National Academy of Sciences.

Correction for d'Errico et al., Additional evidence on the use of personal ornaments in the Middle Paleolithic of North Africa

S. Doran, W. Shipe, M. Seager, 2009, Proceedings of the National Academy of Sciences.

The muscarinic M1 receptor positive allosteric modulator PQCA improves cognitive measures in rat, cynomolgus macaque, and rhesus macaque

Jason M. Uslaner, William J. Ray, Michelle Pearson, 2012, Psychopharmacology.

Human Alzheimer’s disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology

J. Klappenbach, C. Mirescu, V. Malkov, 2018, Journal of Neuroinflammation.

A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats.

Gary Lee, M. Niosi, Gang Wu, 2004, European journal of pharmacology.

MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy

Lynn A. Hyde, E. Hostetler, J. Uslaner, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy

J. Uslaner, Sean M. Smith, J. Hess, 2018, PloS one.

Discovery of MK-8719, A Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies.

D. Klein, J. Hess, D. Vocadlo, 2019, Journal of medicinal chemistry.

The muscarinic M1 receptor positive allosteric modulator PQCA improves cognitive measures in rat, cynomolgus macaque, and rhesus macaque

J. Uslaner, S. Kuduk, J. Vivian, 2012, Psychopharmacology.

Human Alzheimer’s disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology

J. Klappenbach, C. Mirescu, V. Malkov, 2018, Journal of Neuroinflammation.

Pharmacology of 2-[4-(4-Chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: A Potent, Broad-Spectrum State-Dependent Sodium Channel Blocker for Treating Pain States

R. B. Carter, J. Pomonis, D. Hogenkamp, 2006, Journal of Pharmacology and Experimental Therapeutics.

EARLY CLINICAL RESULTS AND PRECLINICAL VALIDATION OF THE O-GLCNACASE (OGA) INHIBITOR MK-8719 AS A NOVEL THERAPEUTIC FOR THE TREATMENT OF TAUOPATHIES

Dawn M. Toolan, Joseph James Duffy, J. Renger, 2016, Alzheimer's & Dementia.