Moran Sun

发表

Discovery of a novel piperlongumine analogue as a microtubule polymerization inhibitor with potent anti-angiogenic and anti-metastatic efficacy.

H. Yang, Yixin Zhang, Y. Duan, 2022, European journal of medicinal chemistry.

Concise synthesis of 2-methoxyestradiol through C(sp2)-H methoxylation

Hong-min Liu, Y. Duan, Moran Sun, 2020, Steroids.

Enantiospecific total synthesis of (+)-tanikolide via a key [2,3]-Meisenheimer rearrangement with an allylic amine N-oxide-directed epoxidation and a one-pot trichloroisocyanuric acid N-debenzylation and N-chlorination.

Hua Yang, Hang Zhou, K. Gao, 2013, The Journal of organic chemistry.

Concise synthesis of 2-methoxyestradiol from 17β-estradiol through the C(sp2)-H hydroxylation

Mengyu Ba, Qing Zhao, Hong-liang Li, 2019, Steroids.

Construction of chiral tertiary alcohol stereocenters via the [2,3]-Meisenheimer rearrangement: enantioselective synthesis of the side-chain acids of homoharringtonine and harringtonine.

Hua Yang, Moran Sun, Ming-Chao Zhu, 2013, The Journal of organic chemistry.

Highly efficient formal synthesis of cephalotaxine, using the Stevens rearrangement--acid lactonization sequence as a key transformation.

Hong-min Liu, Hua Yang, Hong Lu, 2009, The Journal of organic chemistry.

Triazol: a privileged scaffold for proteolysis targeting chimeras.

Y. Duan, Mengyu Ba, Yongfang Yao, 2019, Future medicinal chemistry.

Design, synthesis and biological evaluation of novel tubulin inhibitors targeting colchicine sites.

H. Yang, Y. Duan, Jinling Qin, 2023, Bioorganic & medicinal chemistry letters.

Angiogenesis, Anti-Tumor, and Anti-Metastatic Activity of Novel α-Substituted Hetero-Aromatic Chalcone Hybrids as Inhibitors of Microtubule Polymerization

Yixin Zhang, Y. Duan, Mo-ran Sun, 2021, Frontiers in Chemistry.

Enantiospecific synthesis of methyl ester side chain of bishomoharringtonine

Hua Yang, Jiaxin Zheng, K. Gao, 2015, Research on Chemical Intermediates.

Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors

Yixin Zhang, Y. Duan, Mo-ran Sun, 2022, Journal of enzyme inhibition and medicinal chemistry.

The role of MOZ/KAT6A in hematological malignancies and advances in MOZ/KAT6A inhibitors.

Xuan Wang, Y. Duan, Yongfang Yao, 2021, Pharmacological research.

Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.

Yixin Zhang, Y. Duan, Jinling Qin, 2021, European journal of medicinal chemistry.

Design, synthesis, and biological activity evaluation of novel tubulin polymerization inhibitors based on pyrimidine ring skeletons.

H. Yang, Y. Duan, Jinling Qin, 2023, Bioorganic & medicinal chemistry letters.

A Concise and Scalable Formal Synthesis of the Enantiopure Side-Chain Diester of Homoharringtonine

Hua Yang, Yaowen Lai, Xin Jia, 2015 .

2-Methoxydiol derivatives as new tubulin and HDAC dual-targeting inhibitors, displaying antitumor and antiangiogenic response.

Yixin Zhang, Y. Duan, Mo-ran Sun, 2022, Bioorganic chemistry.

APJ/apelin: a promising target for the treatment of retinopathy of prematurity.

Y. Duan, Yongfang Yao, Moran Sun, 2022, Drug discovery today.

Discovery of N-(2-oxoethyl) sulfanilamide-derived inhibitors of KAT6A (MOZ) against leukemia by an isostere strategy.

Y. Duan, Yongfang Yao, Chuanjun Song, 2023, European journal of medicinal chemistry.

Characterization, pharmacokinetics, tissue distribution and antitumor activity of honokiol submicron lipid emulsions in tumor-burdened mice.

Qiang Li, Jie Zhou, Yujie Tang, 2013, Die Pharmazie.

Discovery of the cereblon-recruiting tubulin PROTACs effective in overcoming Taxol resistance in vitro and in vivo.

Jinling Qin, Yongfang Yao, Moran Sun, 2023, European journal of medicinal chemistry.

Synthesis and biological evaluation of 4-phenyl-5-quinolinyl substituted isoxazole analogues as potent cytotoxic and tubulin polymerization inhibitors against ESCC.

Moran Sun, Yuanyuan Pei, Na Li, 2024, European journal of medicinal chemistry.