G. Otter

发表

Eicosanoids and metastasis: experimental aspects in Lewis lung carcinoma.

R. Karmali, K. Choi, F. Schmid, 1986, Cancer biochemistry biophysics.

New folate analogs of the 10-deaza-aminopterin series: markedly increased antitumor activity of the 10-ethyl analog compared to the parent compound and methotrexate against some human tumor xenografts in nude mice.

F. Sirotnak, F. Schmid, J. Degraw, 1985, Cancer treatment reports.

Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen with leucovorin rescue against metastatic murine solid tumors.

F. Sirotnak, F. Schmid, G. Otter, 1993, Cancer research.

Studies on analogues of classical antifolates bearing the naphthoyl group in place of benzoyl in the side chain.

C. Johnson, J. Maddry, J. McGuire, 1993, Journal of medicinal chemistry.

Synthesis and in vitro cytotoxicity of 6-vinyluridine and related compounds

R. Klein, S. Megati, B. Otter, 1994 .

Analogues of 10-deazaaminopterin and 5-alkyl-5,10-dideazaaminopterin with the 4-substituted 1-naphthoyl group in the place of 4-substituted benzoyl.

C. Johnson, B. Ramamurthy, J. R. Piper, 1996, Journal of medicinal chemistry.

Synthesis and antifolate evaluation of 10-ethyl-5-methyl-5,10- dideazaaminopterin and an alternative synthesis of 10-ethyl-10- deazaaminopterin (edatrexate).

C. Johnson, J. R. Piper, G. Otter, 1992, Journal of medicinal chemistry.

Analogs of tetrahydrofolate directed at folate-dependent purine biosynthetic enzymes. Characteristics of mediated entry and transport-related resistance in L1210 cells for 5,10-dideazatetrahydrofolate and two 10-alkyl derivatives.

F. Sirotnak, J. Degraw, J. R. Piper, 1988, Biochemical pharmacology.

FURTHER EVALUATION OF 5-ALKYL-5-DEAZA ANTIFOLATES. 5-PROPYL- AND 5-BUTYL-5-DEAZA ANALOGUES OF AMINOPTERIN AND METHOTREXATE

J. Maddry, B. Ramamurthy, J. R. Piper, 1995 .

Analogues of classical antifolates bearing naphthoyl in place of benzoyl.

C. Johnson, J. Maddry, J. McGuire, 1993, Advances in experimental medicine and biology.

Cryofragility and other membrane characteristics of solid mouse tumors.

D. Hutchison, F. Schmid, G. Otter, 1981, Cryobiology.

Resistance patterns of Walker carcinosarcoma 256 and other rodent tumors to cyclophosphamide and L-phenylalanine mustard.

C. Stock, F. Schmid, G. Otter, 1980, Cancer research.

ResistancePatterns of Walker Carcinosarcoma256 and Other Rodent Tumors to Cyclophosphamide and L-Phenylalanine Mustard1

C. Stock, F. Schmid, G. Otter, 1980 .

Differential uptake of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea and doxorubicin by Lewis lung carcinoma and Ridgway osteogenic sarcoma.

D. Hutchison, F. S. Philips, F. Schmid, 1983, Cancer research.

Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation.

M. Waltham, B. Schweitzer, J. Bertino, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Disposition of leucovorin and its metabolites in the plasma, intestinal epithelium, and intraperitoneal L1210 cells of methotrexate-pretreated mice

F. Sirotnak, D. Priest, M. Bunni, 2004, Cancer Chemotherapy and Pharmacology.

Schedule-dependent synergism of taxol or taxotere with edatrexate against human breast cancer cells in vitro

T. Chou, F. Sirotnak, Ting-Chao Chou, 1995, Cancer Chemotherapy and Pharmacology.

Effective combination therapy of metastatic murine solid tumors with edatrexate and the vinca alkaloids, vinblastine, navelbine and vindesine

F. Sirotnak, G. Otter, 2004, Cancer Chemotherapy and Pharmacology.

Structural design, biochemical properties, and evidence for improved therapeutic activity of 5-alkyl derivatives of 5-deazaaminopterin and 5-deazamethotrexate compared to methotrexate in murine tumor models.

J. Montgomery, F. Sirotnak, F. Schmid, 1988, Cancer research.

L1210 leukemia hybrids isolated after fusion of alkylating agent-resistant sublines.

I. Hirano, F. Schmid, G. Otter, 1988, Leukemia research.

Combination chemotherapy with a new folate analog: activity of 10-ethyl-10-deaza-aminopterin compared to methotrexate with 5-fluorouracil and alkylating agents against advanced metastatic disease in murine tumor models.

F. Sirotnak, F. Schmid, J. Degraw, 1987, Cancer treatment reports.

Further evaluation of bimolane and analogs as potential antitumor agents.

Y. Ren, F. Schmid, G. Otter, 1985, European journal of cancer & clinical oncology.

Mutagenic and chemotherapeutic activity in L1210 leukemia of several monofunctional alkylating agents.

F. Schmid, B. Mehta, G. Otter, 1985, Cancer research.

Drug sensitivity of methylnitrosourea- and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea-resistant L1210 lines.

F. Schmid, C. F. Chen, G. Otter, 1986, Cancer Research.

Steam sterilisation of sandpits infected with toxocara eggs.

F. van Knapen, J. Franchimont, G. Otter, 1979, British medical journal.