U. Horsten

发表

Combining Two Mutations of Human Interleukin-6 That Affect gp130 Activation Results in a Potent Interleukin-6 Receptor Antagonist on Human Myeloma Cells (*)

S. Rose-John, A. Wollmer, J. Grötzinger, 1995, The Journal of Biological Chemistry.

Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.

G. Ciliberto, I. Kerr, P. Heinrich, 1998, The Biochemical journal.

IL-6 Antagonistic Activity of Soluble gp130 on Soluble IL-6 Receptor Potentiates the

P. Heinrich, G. Müller-Newen, J. Wijdenes, 1998 .

Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes.

P. Heinrich, G. Müller-Newen, J. Grötzinger, 1999, Journal of immunology.

Signal Transducer Glycoprotein 130 Extracellular Domains for Activation of the Importance of the Membrane-Proximal Tacken

P. Heinrich, I. Kurth, S. Pflanz, 1999 .

Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses.

P. Heinrich, G. Müller-Newen, J. Wijdenes, 1998, Journal of immunology.

Molecular Modeling-guided Mutagenesis of the Extracellular Part of gp130 Leads to the Identification of Contact Sites in the Interleukin-6 (IL-6)·IL-6 receptor·gp130 Complex*

P. Heinrich, G. Müller-Newen, A. Wollmer, 1997, The Journal of Biological Chemistry.

The membrane distal half of gp130 is responsible for the formation of a ternary complex with IL‐6 and the IL‐6 receptor

P. Heinrich, S. Rose-John, J. Müllberg, 1995, FEBS letters.

Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis.

P. Heinrich, G. Müller-Newen, S. Minvielle, 1999, European journal of biochemistry.

Importance of the Membrane-Proximal Extracellular Domains for Activation of the Signal Transducer Glycoprotein 1301

P. Heinrich, G. Müller-Newen, I. Kurth, 2000, The Journal of Immunology.