Agnieszka Marcinowicz

发表

Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1

Lifu Wang, C. Link, Sanjeev Kumar, 2020, Oncotarget.

Discovery of indoximod prodrugs and characterization of clinical candidate NLG802.

C. Link, Sanjeev Kumar, E. Brincks, 2020, European journal of medicinal chemistry.

Discovery of Clinical Candidate (1 R,4 r)-4-(( R)-2-(( S)-6-Fluoro-5 H-imidazo[5,1- a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a Potent and Selective Inhibitor of Indoleamine 2,3-Dioxygenase 1.

Sanjeev Kumar, S. Harris, R. Metz, 2019, Journal of medicinal chemistry.

Abstract 4076: A novel prodrug of indoximod with enhanced pharmacokinetic properties

C. Link, Sanjeev Kumar, E. Brincks, 2017 .

Multiple global conformational states of the hexameric RepA helicase of plasmid RSF1010 with different ssDNA-binding capabilities are induced by different numbers of bound nucleotides. Analytical ultracentrifugation and dynamic light scattering studies.

M. Jezewska, W. Bujalowski, Agnieszka Marcinowicz, 2008, Journal of molecular biology.

Structure of the tertiary complex of the RepA hexameric helicase of plasmid RSF1010 with the ssDNA and nucleotide cofactors in solution.

M. Jezewska, W. Bujalowski, Paul J. Bujalowski, 2007, Biochemistry.

US FDA 505(b)(2) NDA clinical, CMC and regulatory strategy concepts to expedite drug development.

W. Salminen, O. Aloba, Agnieszka Marcinowicz, 2023, Drug discovery today.

Complexation of tetrapropoxycalix[4]arene with uracil and adenine derivatives in water-containing solution

J. Poznański, V. Kalchenko, A. Solovyov, 2003 .

DNA polymerase X from African swine fever virus: quantitative analysis of the enzyme-ssDNA interactions and the functional structure of the complex.

M. Jezewska, W. Bujalowski, A. Lucius, 2006, Journal of molecular biology.