B. A. Meyers

发表

Discovery of 6-[(3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor.

P. Mandal, Jason P. Burke, F. Mseeh, 2021, Journal of medicinal chemistry.

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.

R. DePinho, M. Warmoes, F. Mseeh, 2019, Cell reports.

Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

Justin K. Huang, P. Mandal, Jason P. Burke, 2020, Cancer Research.

ΔNp63/DGCR8-Dependent MicroRNAs Mediate Therapeutic Efficacy of HDAC Inhibitors in Cancer.

K. Tsai, P. Gunaratne, C. Coarfa, 2016, Cancer cell.