Sylvie Gomez

发表

The discovery and optimisation of pyrido[2,3-d]pyrimidine-2,4-diamines as potent and selective inhibitors of mTOR kinase.

Lisa L. Smith, I. Hickson, G. Smith, 2009, Bioorganic & medicinal chemistry letters.

Identification and optimisation of novel and selective small molecular weight kinase inhibitors of mTOR.

I. Hickson, G. Smith, G. Hermann, 2009, Bioorganic & medicinal chemistry letters.

Novel alkoxybenzamide inhibitors of poly(ADP-ribose) polymerase.

N. Martin, G. Smith, K. Menear, 2008, Bioorganic & medicinal chemistry letters.

4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.

A. Lau, M. O’Connor, C. Knights, 2008, Journal of medicinal chemistry.

Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase.

Krystyna J. Dillon, N. Martin, G. Smith, 2005, Bioorganic & medicinal chemistry letters.

8-Aryl xanthines potent inhibitors of phosphodiesterase 5.

Stephen P. Jelfs, M. Zurini, R. Naef, 2002, Bioorganic & medicinal chemistry letters.

Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: the discovery of AZD8055 and AZD2014.

Linette Ruston, M. Hummersone, K. Pike, 2013, Bioorganic & medicinal chemistry letters.

Potent and selective xanthine-based inhibitors of phosphodiesterase 5.

M. Zurini, R. Naef, S. Watson, 2007, Bioorganic & medicinal chemistry letters.

Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: the discovery of AZD8055 and AZD2014.

Linette Ruston, M. Hummersone, K. Pike, 2013, Bioorganic & medicinal chemistry letters.

The discovery and optimisation of pyrido[2,3-d]pyrimidine-2,4-diamines as potent and selective inhibitors of mTOR kinase.

Lisa L. Smith, I. Hickson, G. Smith, 2009, Bioorganic & medicinal chemistry letters.