Steven J Shire

发表

Formulation and manufacturability of biologics.

Steven J Shire, S. Shire, 2009, Current opinion in biotechnology.

Specific interactions in high concentration antibody solutions resulting in high viscosity.

Sandeep Yadav, Steven J Shire, Jun Liu, 2010, Journal of pharmaceutical sciences.

Coarse-grained modeling of the self-association of therapeutic monoclonal antibodies.

Gregory A Voth, Tim J Kamerzell, Steven J Shire, 2012, The journal of physical chemistry. B.

The influence of charge distribution on self-association and viscosity behavior of monoclonal antibody solutions.

Sandeep Yadav, Steven J Shire, T. Laue, 2012, Molecular pharmaceutics.

Weak interactions govern the viscosity of concentrated antibody solutions: high-throughput analysis using the diffusion interaction parameter.

Sandeep Yadav, Steven J Shire, Barthélemy Demeule, 2012, Biophysical journal.

Reversible self-association of a concentrated monoclonal antibody solution mediated by Fab-Fab interaction that impacts solution viscosity.

Steven J Shire, Thomas W Patapoff, Jun Liu, 2008, Journal of pharmaceutical sciences.

Small-angle neutron scattering characterization of monoclonal antibody conformations and interactions at high concentrations.

Yatin Gokarn, Norman J Wagner, Steven J Shire, 2013, Biophysical journal.

Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution.

Steven J Shire, Jun Liu, S. Shire, 2005, Journal of pharmaceutical sciences.

Monoclonal antibody self-association, cluster formation, and rheology at high concentrations.

Sandeep Yadav, Steven J Shire, S. Shire, 2013, The journal of physical chemistry. B.

Increasing IgG concentration modulates the conformational heterogeneity and bonding network that influence solution properties.

Tim J Kamerzell, Steven J Shire, Y John Wang, 2009, The journal of physical chemistry. B.

Challenges in the development of high protein concentration formulations.

Steven J Shire, Jun Liu, Z. Shahrokh, 2004, Journal of pharmaceutical sciences.

Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies.

Sandeep Yadav, Steven J Shire, D. Kalonia, 2010, Journal of pharmaceutical sciences.

The role of amino acid sequence in the self-association of therapeutic monoclonal antibodies: insights from coarse-grained modeling.

Gregory A Voth, Sandeep Yadav, Steven J Shire, 2013, The journal of physical chemistry. B.

Viscosity behavior of high-concentration monoclonal antibody solutions: correlation with interaction parameter and electroviscous effects.

Sandeep Yadav, Steven J Shire, D. Kalonia, 2012, Journal of pharmaceutical sciences.

Use of dynamic light scattering to determine second virial coefficient in a semidilute concentration regime.

Sandeep Yadav, Steven J Shire, D. Kalonia, 2011, Analytical biochemistry.