Neil Kaplowitz

发表

Mechanistic agent-based damage and repair models as hypotheses for patterns of necrosis caused by drug induced liver injury

Glen E. P. Ropella, C. Anthony Hunt, Andrew K. Smith, 2014, SummerSim.

Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments

Glen E. P. Ropella, C. Anthony Hunt, Andrew K. Smith, 2016, PLoS Comput. Biol..

Dealing with stress

Neil Kaplowitz, N. Kaplowitz, 2012, Hepatology.

Virtual experiments help explain intra- and inter-strain variability of AILI-induced hepatic necrosis in mice

Glen E. P. Ropella, C. Anthony Hunt, Andrew K. Smith, 2016, SpringSim.

Metabonomic investigation of liver profiles of nonpolar metabolites obtained from alcohol-dosed rats and mice using high mass accuracy MSn analysis.

Cheng Ji, Neil Kaplowitz, Georgios Theodoridis, 2011, Journal of proteome research.

Herb-Induced Liver Injury: A Global Concern

Neil Kaplowitz, N. Kaplowitz, 2018, Chinese Journal of Integrative Medicine.

Idiosyncratic drug hepatotoxicity

Neil Kaplowitz, N. Kaplowitz, 2005, Nature Reviews Drug Discovery.

Drug-Induced Liver Disease

Neil Kaplowitz, N. Kaplowitz, L. DeLeve, 2002 .

Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor‐α–induced apoptosis in cultured mouse hepatocytes

Neil Kaplowitz, Guoping Feng, N. Kaplowitz, 2002, Hepatology.

Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury*

Neil Kaplowitz, N. Kaplowitz, Derick Han, 2008, Journal of Biological Chemistry.

Principles of Clinical Gastroenterology

Neil Kaplowitz, Anthony N. Kalloo, A. Kalloo, 2008 .

Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications

Neil Kaplowitz, N. Kaplowitz, Zhang-Xu Liu, 2016, Liver international : official journal of the International Association for the Study of the Liver.

Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis

Neil Kaplowitz, K. Ishak, W. Black, 1981, Hepatology.

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial.

Neil Kaplowitz, Paul B Watkins, P. Watkins, 2006, JAMA.

Effect of glutathione depletion on sites and topology of superoxide and hydrogen peroxide production in mitochondria.

Neil Kaplowitz, N. Kaplowitz, Derick Han, 2003, Molecular pharmacology.

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria.

Neil Kaplowitz, Liyun Yuan, Sanda Win, 2013, Trends in pharmacological sciences.

The Clinical Liver Safety Assessment Best Practices Workshop: Rationale, Goals, Accomplishments and the Future

Neil Kaplowitz, Michael Merz, Paul B. Watkins, 2014, Drug Safety.

Cell death and cell death responses in liver disease: mechanisms and clinical relevance.

Neil Kaplowitz, Tom Luedde, T. Luedde, 2014, Gastroenterology.

Liver biology and pathobiology

Neil Kaplowitz, N. Kaplowitz, 2006, Hepatology.

Current Challenges and Controversies in Drug-Induced Liver Injury

Neil Kaplowitz, Paul B Watkins, P. Watkins, 2012, Drug Safety.