A. Rosato

发表

Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors

C. Grimm, G. Vollmer, F. Bracher, 2021, Scientific Reports.

Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2

A. Vollmar, K. Umehara, Cheng-Chang Chen, 2021, Scientific Reports.

Two-pore and TRPML cation channels: Regulators of phagocytosis, autophagy and lysosomal exocytosis.

C. Grimm, A. Rosato, R. Tang, 2020, Pharmacology & therapeutics.

Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

T. Gudermann, Cheng-Chang Chen, C. Grimm, 2022, Nature Communications.

TRPML1: Role In Autophagy And Potential Target To Treat Lysosomal Storage Disorders

A. Rosato, 2018 .

TRPMLs and TPCs: Targets for lysosomal storage and neurodegenerative disease therapy?

C. Grimm, A. Rosato, Einar K Krogsaeter, 2022, Cell calcium.

Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes

C. Grimm, Taufiq Rahman, S. Bolsover, 2022, Nature Communications.

Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

T. Gudermann, Cheng-Chang Chen, C. Grimm, 2022, Nature Communications.

TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial cells

C. Grimm, M. Schweizer, G. Hermey, 2023, bioRxiv.

TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway

A. Ballabio, C. Grimm, D. Medina, 2019, Nature Communications.