Susanne Gerndt

Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors

C. Grimm, G. Vollmer, F. Bracher, 2021, Scientific Reports.

Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3.

Cheng-Chang Chen, C. Grimm, M. Schaefer, 2020, European journal of medicinal chemistry.

Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function

Meghan T. Miller, T. Gudermann, A. Vollmar, 2020, eLife.

Racemic total synthesis and evaluation of the biological activities of the isoquinoline–benzylisoquinoline alkaloid muraricine

F. Bracher, Martin Müller, Karin Bartel, 2020, Archiv der Pharmazie.

Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth.

S. Zahler, A. Vollmar, Cheng-Chang Chen, 2021, Cell chemical biology.

Discovery of lipophilic two‐pore channel agonists

C. Grimm, F. Bracher, Susanne Gerndt, 2020, The FEBS journal.

The lysosomotrope GPN mobilises Ca2+ from acidic organelles

A. Schapira, C. Grimm, F. Bracher, 2021, Journal of Cell Science.