Michael C Chang

Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models

Shristi Pandey, Tiffany Wu, T. Singh, 2022, Nature Aging.

Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.

Melanie A. Huntley, J. Elstrott, M. Hedehus, 2019, Cell reports.

Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation

Z. Modrušan, J. Kaminker, Karpagam Srinivasan, 2017, The Journal of experimental medicine.

The Role of the Complement Pathway in Clinical Progression of Geographic Atrophy

L. Honigberg, Verena Steffen, R. Edmonds, 2023, Ophthalmology science.

Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights APOL1 as a high risk locus in patients with diabetic macular edema

M. McCarthy, B. Yaspan, A. Mahajan, 2023, medRxiv.

Alternative Complement Pathway Inhibition by Lampalizumab

L. Honigberg, Verena Steffen, R. Edmonds, 2023, Ophthalmology science.