D. Cox

发表

Selective Olefin Reduction in Thebaine Using Hydrazine Hydrate and O2 under Intensified Continuous Flow Conditions

C. Kappe, Bartholomäus Pieber, C. Kappe, 2016 .

Design and Development of Pd-Catalyzed Aerobic N-Demethylation Strategies for the Synthesis of Noroxymorphone in Continuous Flow Mode

C. Kappe, David Cantillo, Bernhard Gutmann, 2017 .

Study on the Activation of the Opioid Receptors by a Set of Morphine Derivatives in a Well-Defined Assay System

O. Civelli, Zhiwei Wang, Yan Zhang, 2011, Neurochemical Research.

Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium‐Catalyzed N‐Demethylation/Acylation and/or Concomitant O‐Demethylation

T. Hudlický, Aleš Machara, M. A. Endoma-Arias, 2012 .

Direct Synthesis of Naltrexone by Palladium-Catalyzed N-Demethylation/Acylation of Oxymorphone: The Benefit of CH Activation and the Intramolecular Acyl Transfer from C-14 Hydroxy

T. Hudlický, Aleš Machara, D. Cox, 2012 .

General Method of Synthesis for Naloxone, Naltrexone, Nalbuphone, and Nalbuphine by the Reaction of Grignard Reagents with an Oxazolidine Derived from Oxymorphone

T. Hudlický, M. A. Endoma-Arias, D. Cox, 2013 .

Palladium‐Catalyzed N‐Demethylation/N‐Acylation of Some Morphine and Tropane Alkaloids

T. Hudlický, Hannes G. Leisch, Eric Scocchera, 2008 .

Heteroatom analogues of hydrocodone: synthesis and biological activity.

T. Hudlický, S. Cutler, C. McCurdy, 2013, The Journal of organic chemistry.

Batch- and Continuous-Flow Aerobic Oxidation of 14-Hydroxy Opioids to 1,3-Oxazolidines-A Concise Synthesis of Noroxymorphone.

Bernhard Gutmann, Ulrich Weigl, C. Kappe, 2016, Chemistry.

Synthesis of Naltrexone and (R)-Methylnaltrexone from Oripavine via Direct Oxidation of Its Quaternary Salts

T. Hudlický, D. Adams, Hannes G. Leisch, 2015, Synlett.

Conversion of Thebaine to Oripavine and Other Useful Intermediates for the Semisynthesis of Opiate‐Derived Agents: Synthesis of Hydromorphone

T. Hudlický, T. Stamatatos, Aleš Machara, 2014 .

Synthesis of buprenorphine from oripavine via N-demethylation of oripavine quaternary salts.

T. Hudlický, D. Adams, Aleš Machara, 2011, The Journal of organic chemistry.

Synthesis of Nororipavine and Noroxymorphone via N- and O-Demethylation of Iron Tricarbonyl Complex of Thebaine

T. Hudlický, I. Císařová, Aleš Machara, 2016, Synthesis.

Direct Synthesis of Noroxymorphone from Thebaine: Unusual CeIV Oxidation of a Methoxydiene‐Iron Complex to an Enone‐γ‐Nitrate

T. Hudlický, I. Císařová, Aleš Machara, 2016 .

Direct Synthesis of Noroxymorphone from Thebaine: Unusual CeIV Oxidation of a Methoxydiene‐Iron Complex to an Enone‐γ‐nitrate.

T. Hudlický, I. Císařová, Aleš Machara, 2016 .

Unexpected N‐Demethylation of Oxymorphone and Oxycodone N‐Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone

T. Hudlický, D. Adams, Aleš Machara, 2012 .

BIOTRANSFORMATIONS OF MORPHINE ALKALOIDS BY FUNGI: N-DEMETHYLATIONS, OXIDATIONS, AND REDUCTIONS

T. Hudlický, Alena Moudra, Hannes G. Leisch, 2009 .

One-pot conversion of thebaine to hydrocodone and synthesis of neopinone ketal.

T. Hudlický, Hannes G. Leisch, R. J. Carroll, 2009, The Journal of organic chemistry.

Two orthorhombic polymorphs of hydromorphone

J. Mazurek, J. Sasine, D. Cox, 2016, Acta crystallographica. Section E, Crystallographic communications.

Toward the Synthesis of Noroxymorphone via Aerobic Palladium-Catalyzed Continuous Flow N-Demethylation Strategies

D. Roberge, C. Kappe, Bernhard Gutmann, 2016 .

Study on the Activation of the Opioid Receptors by a Set of Morphine Derivatives in a Well-Defined Assay System

O. Civelli, Zhiwei Wang, Yan Zhang, 2012, Neurochemical Research.

Studies on regioselective hydrogenation of thebaine and its conversion to hydrocodone

T. Hudlický, Hannes G. Leisch, R. J. Carroll, 2007 .

Synthesis of Nororipavine and Noroxymorphone via N- and O-Demethylation of Iron Tricarbonyl Complex of Thebaine

T. Hudlický, I. Císařová, Aleš Machara, 2016, Synthesis.

SYNTHESIS OF NALBUPHINE FROM ORIPAVINE VIA N-DEMETHYLATION OF N-CYCLOBUTYLMETHYL ORIPAVINE (Dedicated to Dr. Albert Padwa on his 75th birthday)

T. Hudlický, Aleš Machara, D. Cox, 2012 .

Synthesis of Nalbuphine from Oripavine via N-Demethylation of N-Cyclobutylmethyl Oripavine.

T. Hudlický, Aleš Machara, D. Cox, 2012 .