K. Ishikawa

Chronic administration of the metastin/kisspeptin analog KISS1-305 or the investigational agent TAK-448 suppresses hypothalamic pituitary gonadal function and depletes plasma testosterone in adult male rats.

C. Kitada, Y. Takatsu, Atsuko Suzuki, 2012, Endocrinology.

Reduced responsiveness of kisspeptin neurons to estrogenic positive feedback associated with age-related disappearance of LH surge in middle-age female rats.

H. Matsumoto, Kiyoshi Matsumoto, G. Watanabe, 2013, General and comparative endocrinology.

Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK-448, for its anti-tumor efficacy in a rat xenograft model.

J. DeJongh, S. Asahi, H. Matsui, 2020, Biopharmaceutics & drug disposition.

Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK‐448, in quantitatively evaluating anti‐tumor growth effect in the rat VCaP androgen‐sensitive prostate cancer model

A. Tanaka, Tatsuya Watanabe, H. Matsui, 2018, European journal of pharmacology.

Effect of clinofibrate, a new hypolipidemic agent, on biliary and serum lipids in patients with hyperlipidemia.

G. Kajiyama, M. Fujiyama, H. Kukita, 1982, Atherosclerosis.

An administration of TAK-683 at a minimally effective dose for luteinizing hormone stimulation under the absence of the ovary induces luteinizing hormone surge in ovary-intact goats

S. Ohkura, H. Okamura, H. Matsumoto, 2017, The Journal of reproduction and development.