K. Meagher

A novel bispecific antibody platform to direct complement activity for efficient lysis of target cells

L. Macdonald, A. Murphy, N. Stahl, 2019, Scientific Reports.

Humanization of T cell–mediated immunity in mice

A. Dhanik, L. Macdonald, A. Murphy, 2021, Science Immunology.

Humanized C3 Mouse: A Novel Accelerated Model of C3 Glomerulopathy.

L. Macdonald, A. Murphy, Yi Wei, 2020, Journal of the American Society of Nephrology : JASN.

Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties

L. Macdonald, A. Murphy, G. Yancopoulos, 2019, Proceedings of the National Academy of Sciences.

Evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy disease: an open-label phase 2 and 3 study

P. Chatchatee, K. Suphapeetiporn, J. Jalbert, 2024, The Lancet.

25 A phase 2/3 study evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy (CHAPLE disease)

M. Lenardo, P. Chatchatee, Helen F. Matthews, 2023, Immunobiology.