Yafei Huang

RORγt agonist enhances anti-PD-1 therapy by promoting monocyte-derived dendritic cells through CXCL10 in cancers

K. Yu, Zhongen Wu, Ming-cheng Yu, 2022, Journal of experimental & clinical cancer research : CR.

Discovery of carboxyl-containing biaryl ureas as potent RORγt inverse agonists.

Yonghui Wang, Hui-min Guo, Ming-cheng Yu, 2020, European journal of medicinal chemistry.

Discovery of carbazole carboxamides as novel RORγt inverse agonists.

Wei-Chang Fu, Yonghui Wang, Ming-cheng Yu, 2018, European journal of medicinal chemistry.

Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors.

J. D. Elliott, Yonghui Wang, Zhijun Xiang, 2015, ACS medicinal chemistry letters.

Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity.

Yonghui Wang, Shijie Chen, Ming-cheng Yu, 2023, European journal of medicinal chemistry.

Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (RORγt) modulators: insights into different protein behaviors with “short” and “long” inverse agonists

Xiao-min Luo, C. Luo, Shijie Chen, 2020, Acta Pharmacologica Sinica.

Discovery of tetrahydroquinolines and benzomorpholines as novel potent RORγt agonists.

Yonghui Wang, Hui-min Guo, Ming-cheng Yu, 2020, European journal of medicinal chemistry.

From RORγt Agonist to Two Types of RORγt Inverse Agonists.

Yonghui Wang, M. Lobera, Zhijun Xiang, 2018, ACS medicinal chemistry letters.

Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy.

Yonghui Wang, Ming-cheng Yu, Yunpeng Zhao, 2023, Journal of medicinal chemistry.