Shahenda M. El-Messery

发表

New Benzimidazoles Targeting Breast Cancer: Synthesis, Pin1 Inhibition, 2D NMR Binding, and Computational Studies

Morkos A. Henen, M. Henen, H. Eisa, 2022, Molecules.

Design, synthesis and computational study of new benzofuran hybrids as dual PI3K/VEGFR2 inhibitors targeting cancer

Morkos A. Henen, M. Henen, M. A. El-Sayed, 2022, Scientific Reports.

Design and Synthesis of Benzene Homologues Tethered with 1,2,4-Triazole and 1,3,4-Thiadiazole Motifs Revealing Dual MCF-7/HepG2 Cytotoxic Activity with Prominent Selectivity via Histone Demethylase LSD1 Inhibitory Effect

Saleh K. Ihmaid, Hany E. A. Ahmed, Mosa Alsehli, 2022, International journal of molecular sciences.

Synthesis, biological evaluation and molecular modeling study of [1,2,4]-Triazolo[4,3-c]quinazolines: New class of EGFR-TK inhibitors.

M. N. Nasr, Shahenda M. El-Messery, Wafaa A. Ewes, 2020, Bioorganic & medicinal chemistry.

Synthesis, state-of-the-art NMR-binding and molecular modeling study of new benzimidazole core derivatives as Pin1 inhibitors: Targeting breast cancer.

Morkos A. Henen, M. Henen, H. Eisa, 2020, Bioorganic & medicinal chemistry.

Novel Pyruvate Kinase (PK) Inhibitors: New Target to Overcome Bacterial Resistance

Ghada S. Hassan, R. Khattab, Mardia T. El Sayed, 2020 .

New benzimidazole based hybrids: Synthesis, molecular modeling study and anticancer evaluation as TopoII inhibitors.

Amany S. Mostafa, Shahenda M. El-Messery, Nareman A. Nawareg, 2022, Bioorganic chemistry.

Design, Synthesis, Antimicrobial Evaluation and Molecular Modeling Study of 1,2,4-Triazole-Based 4-Thiazolidinones

M. Al-agamy, H. Abdel-Rahman, Sahar Ahmed, 2016, Molecules.

Tetrahydroindolocarbazoles (THICZs) as new class of urokinase (uPA) inhibitors: Synthesis, anticancer evaluation, DNA-damage determination, and molecular modelling study.

Mohamed El-Naggar, Mamdouh M. Ali, Abeer E E Mahmoud, 2018, Bioorganic chemistry.

New Thiazolopyrimidine as anticancer agents: Synthesis, biological evaluation, DNA binding, Molecular modeling and ADMET study.

Ghada S. Hassan, Sara T. A. Al-Rashood, Moataz A. Shaldam, 2020, Bioorganic & medicinal chemistry letters.

DNA binding studies of novel diazatruxenones analogs as potential anticancer agents: Synthesis, antitumor investigation, DNA binding, SAR and molecular modeling calculation.

Ghada S. Hassan, Mardia T. El Sayed, S. M. El-Sayed, 2020, Bioorganic chemistry.

Towards breast cancer targeting: Synthesis of tetrahydroindolocarbazoles, antibreast cancer evaluation, uPA inhibition, molecular genetic and molecular modelling studies.

Ghada S. Hassan, Mohamed El-Naggar, Mamdouh M. Ali, 2019, Bioorganic chemistry.

Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study.

K. Mohamed, Ghada S. Hassan, W. Fayad, 2013, European journal of medicinal chemistry.

Synthesis, antimicrobial, anti-biofilm evaluation, and molecular modelling study of new chalcone linked amines derivatives

Ghada S. Hassan, Sara T. A. Al-Rashood, E. E. Habib, 2018, Journal of enzyme inhibition and medicinal chemistry.

Substituted thiazoles V. synthesis and antitumor activity of novel thiazolo[2,3-b]quinazoline and pyrido[4,3-d]thiazolo[3,2-a]pyrimidine analogues.

Ghada S. Hassan, Fatmah A. M. Al-Omary, H. El-Subbagh, 2012, European journal of medicinal chemistry.

Synthesis and anticancer activity of new thiazolo[3,2-a]pyrimidines: DNA binding and molecular modeling study.

Ghada S. Hassan, Ahmadi Abbas, Shahenda M. El-Messery, 2017, Bioorganic chemistry.

Nonclassical antifolates, part 5. Benzodiazepine analogs as a new class of DHFR inhibitors: synthesis, antitumor testing and molecular modeling study.

Ghada S. Hassan, Sara T. A. Al-Rashood, Fatmah A. M. Al-Omary, 2014, European journal of medicinal chemistry.

Substituted thiazoles VII. Synthesis and antitumor activity of certain 2-(substituted amino)-4-phenyl-1,3-thiazole analogs.

Ghada S. Hassan, Fatmah A. M. Al-Omary, H. El-Subbagh, 2012, Bioorganic & medicinal chemistry letters.

Substituted thiazoles VI. Synthesis and antitumor activity of new 2-acetamido- and 2 or 3-propanamido-thiazole analogs.

Ghada S. Hassan, Fatmah A. M. Al-Omary, H. El-Subbagh, 2012, European journal of medicinal chemistry.

Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors.

Ghada S. Hassan, Sara T. A. Al-Rashood, M. Nagi, 2014, Bioorganic & medicinal chemistry letters.

Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones.

Ghada S. Hassan, M. Nagi, Fatmah A. M. Al-Omary, 2013, European journal of medicinal chemistry.

Synthesis, biological evaluation and molecular modeling study of some new methoxylated 2-benzylthio-quinazoline-4(3H)-ones as nonclassical antifolates.

Ghada S. Hassan, Sara T. A. Al-Rashood, M. Nagi, 2016, Bioorganic & medicinal chemistry letters.

Synthesis, anticonvulsant activity and molecular modeling study of some new hydrazinecarbothioamide, benzenesulfonohydrazide, and phenacylacetohydrazide analogues of 4(3H)-quinazolinone.

Huda S. A Al-Salem, A. M. Al-Obaid, H. El-Subbagh, 2015, Bioorganic & medicinal chemistry letters.

Synthesis, biological evaluation and molecular modeling study of thiadiazolo[3,2-a][1,3]diazepine analogues of HIE-124 as a new class of short acting hypnotics.

Ghada S. Hassan, H. El-Subbagh, Shahenda M. El-Messery, 2016, European journal of medicinal chemistry.

Synthesis, biological evaluation and molecular modeling study of some new thiazolodiazepine analogs as CNS active agents.

Ghada S. Hassan, Sara T. A. Al-Rashood, H. El-Subbagh, 2016, Bioorganic & medicinal chemistry letters.

Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study.

Morkos A. Henen, M. Henen, M. A. El-Sayed, 2020, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of new curcumin analogues as antioxidant and antitumor agents: molecular modeling study.

H. El-kashef, Mariam A. Ghaly, G. Suddek, 2015, European journal of medicinal chemistry.

SECONDARY METABOLITES FROM RICE CULTURE OF ASPERGILLUS SP. ISOLATED FROM MELALEUCA SUBULATA (CHEEL) CRAVEN LEAVES AND THEIR ANTICANCER ACTIVITY

Reem A. Kamel, R. Ibrahim, F. Moharram, 2020, International Journal of Pharmacy and Pharmaceutical Sciences.

Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3H)-one as DHFR inhibitors.

Ghada S. Hassan, Hanan H. Georgey, M. Raafat, 2017, Bioorganic chemistry.

Synthetic approaches, anticancer potential, HSP90 inhibition, multitarget evaluation, molecular modeling and apoptosis mechanistic study of thioquinazolinone skeleton: Promising antibreast cancer agent.

R. Gomaa, Hamed W. El-Shafey, F. Goda, 2020, Bioorganic chemistry.

Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.

R. Gomaa, Shahenda M El-Messery, Hamed W. El-Shafey, 2020, Bioorganic & medicinal chemistry letters.

Thiadiazolodiazepine analogues as a new class of neuromuscular blocking agents: Synthesis, biological evaluation and molecular modeling study.

Ghada S. Hassan, A. Abdel-Aziz, A. El-Azab, 2017, European journal of medicinal chemistry.

Aspirin is an efficient inhibitor of quorum sensing, virulence and toxins in Pseudomonas aeruginosa.

K. H. Abd El Galil, M. Shaaban, Shahenda M El-Messery, 2014, Microbial pathogenesis.

Targeting microbial resistance: Synthesis, antibacterial evaluation, DNA binding and modeling study of new chalcone-based dithiocarbamate derivatives.

Ghada S. Hassan, H. Alkahtani, Sara T. A. Al-Rashood, 2019, Bioorganic chemistry.

Antibacterial, antibiofilm and molecular modeling study of some antitumor thiazole based chalcones as a new class of DHFR inhibitors.

E. E. Habib, Waad D Alrohily, Shahenda M. El-Messery, 2019, Microbial pathogenesis.

Design, synthesis, and antitumor activity of PLGA nanoparticles incorporating a discovered benzimidazole derivative as EZH2 inhibitor.

Ghada S. Hassan, Sara T. A. Al-Rashood, N. Saleh, 2021, Chemico-biological interactions.

Targeting EGFR tyrosine kinase: Synthesis, in vitro antitumor evaluation, and molecular modeling studies of benzothiazole-based derivatives.

Ghada S. Hassan, Mariam A. Ghaly, Shahenda M. El-Messery, 2020, Bioorganic chemistry.

Minutaside A, new α-amylase inhibitor flavonol glucoside from Tagetes minuta: Antidiabetic, antioxidant, and molecular modeling studies

G. Mohamed, I. A. Shehata, S. Ibrahim, 2015 .

Targeting hepatocellular carcinoma: Synthesis of new pyrazole-based derivatives, biological evaluation, DNA binding, and molecular modeling studies.

F. Badria, Mariam A. Ghaly, E. Abdel‐Latif, 2019, Bioorganic chemistry.

Biphenylpiperazine Based MAO Inhibitors: Synthesis, Biological Evaluation, Reversibility and Molecular Modeling Studies.

F. Goda, Shahenda M. El-Messery, Lamiaa O El-Halaby, 2021, Bioorganic chemistry (Print).

Design and synthesis of indole-based elipticine analogues as topoisomerase IIβ inhibitors

N. Hamdy, Mardia T. El Sayed, S. M. El-Sayed, 2024, Medicinal Chemistry Research.

Benzimidazole Based Hybrids as Privileged Candidates for TopoII Inhibition: Design, Synthesis and Molecular Modeling Studies

Amany S. Mostafa, Shahenda M. El-Messery, Nareman A. Nawareg, 2023, Journal of Molecular Structure.