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Eukaryotic topoisomerase I-mediated cleavage requires bipartite DNA interaction. Cleavage of DNA substrates containing strand interruptions implicates a role for topoisomerase I in illegitimate recombination.

A. Andersen, O. Westergaard, K. Christiansen, 1993, The Journal of biological chemistry.

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange

T. Soldati, A. D. Shapiro, A. B. Svejstrup, 1994, Nature.