Georgia Chenevix-Trench

发表

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.

Jane E. Carpenter, Kyriaki Michailidou, France Labrèche, 2014, Human molecular genetics.

Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome

Michael Dean, Georgia Chenevix-Trench, Susan Shanley, 1996, Cell.

Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource

John L Hopper, Edward Edkins, Phyllis N Butow, 2006, Breast Cancer Research.

Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast

Julian Peto, Matthias W. Beckmann, Peter A. Fasching, 2014, PLoS genetics.

CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies.

Nazneen Rahman, Michael Bremer, Julian Peto, 2004, American journal of human genetics.

Expression of β-Catenin, a Key Mediator of the WNT Signaling Pathway, in Basal Cell Carcinoma

Georgia Chenevix-Trench, G. Chenevix-Trench, M. Cummings, 2000 .

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

Peter Kraft, Todd L Edwards, Nazneen Rahman, 2016, Cancer discovery.

Identification of Novel Genetic Markers of Breast Cancer Survival

Peter Kraft, Nazneen Rahman, Janet A. Dunn, 2015, Journal of the National Cancer Institute.

Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer.

Mark Sherman, Honglin Song, Rebecca Sutphen, 2009, Cancer research.

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Michael Jones, Peter Kraft, Arnaud Droit, 2017, Nature Genetics.

Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics

Peter Kraft, Michael Bremer, Simon S. Cross, 2008, PLoS genetics.

Association of ESR1 gene tagging SNPs with breast cancer risk.

Julian Peto, Ute Hamann, Peter Devilee, 2009, Human molecular genetics.

Evolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1 gene with missense sequence changes and in-frame deletions, but not polymorphisms

Georgia Chenevix-Trench, Sean V Tavtigian, A. Spurdle, 2005, Breast Cancer Research.

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

Rohini Rau-Murthy, Jinghui Zhang, Kenneth Offit, 2013, Nature Genetics.

Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer.

Alun Thomas, Sue Healey, John L Hopper, 2009, American journal of human genetics.

Subtypes of familial breast tumours revealed by expression and copy number profiling

Stephen Fox, Peter Devilee, Peter T. Simpson, 2010, Breast Cancer Research and Treatment.

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation

Matthias W. Beckmann, Peter A. Fasching, Simon S. Cross, 2016, American journal of human genetics.

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers.

Christiana Kartsonaki, Mads Thomassen, Etienne Rouleau, 2011, Human molecular genetics.

BRCA1 and BRCA2 Missense Variants of High and Low Clinical Significance Influence Lymphoblastoid Cell Line Post-Irradiation Gene Expression

Mark Girolami, Amanda B. Spurdle, Piyush Grover, 2008, PLoS genetics.

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

Mads Thomassen, Nina Ditsch, Vijai Joseph, 2012, Breast Cancer Research.

A gene expression prognostic signature for overall survival in patients with high-grade serous ovarian cancer.

Jennifer A. Doherty, Peter A. Fasching, Susan J. Ramus, 2018 .

19p13.1 is a triple-negative-specific breast cancer susceptibility locus.

Daniel J. Park, Julian Peto, Kamila Czene, 2012, Cancer research.

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.

Mads Thomassen, Nina Ditsch, Dieter Niederacher, 2009, Human molecular genetics.

Gene expression profiling of tumour epithelial and stromal compartments during breast cancer progression

Peter T. Simpson, Georgia Chenevix-Trench, Sunil R. Lakhani, 2012, Breast Cancer Research and Treatment.

DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status.

Peter Simpson, Georgia Chenevix-Trench, Anna Marsh, 2010, American journal of human genetics.

Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.

Nandita Mitra, Georgia Chenevix-Trench, Susan L Neuhausen, 2009, Cancer research.

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.

Harvey Risch, Yian A Chen, Mads Thomassen, 2018, Cancer research.

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

Gary D. Bader, Christine L. Clarke, Gary D Bader, 2020, Nature Communications.

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Wei Lu, Wei Zheng, Mads Thomassen, 2013, Nature Genetics.

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.

Dong Liang, Patrick Neven, Harvey Risch, 2016, Journal of the National Cancer Institute.

Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium

Francesmary Modugno, James Paul, Honglin Song, 2015 .

Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk

Mads Thomassen, Julian Peto, Peter A. Fasching, 2013, PLoS genetics.

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

Georgia Chenevix-Trench, Roger L Milne, Fergus J Couch, 2007, Breast Cancer Research.

Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

Patrick Neven, Hui Zhao, Nazneen Rahman, 2012, PloS one.

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

Christiana Kartsonaki, Mads Thomassen, Julian Peto, 2010, Nature Genetics.

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

Patrick Neven, Päivi Heikkilä, Giu-Cheng Hsu, 2011, Human molecular genetics.

Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib

Sean M. Grimmond, Peter T. Simpson, Georgia Chenevix-Trench, 2015, PloS one.

COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration

Peter Kraft, Mads Thomassen, Daniel J. Park, 2013, Breast Cancer Research.

DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Olufunmilayo I. Olopade, Mads Thomassen, Torben A. Kruse, 2014, PLoS genetics.

Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer

Rosemary L. Balleine, Georgia Chenevix-Trench, Craig Luccarini, 2018, Scientific Reports.

Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

Joshua M. Korn, Christiana Kartsonaki, Amanda B. Spurdle, 2010, PLoS Genetics.

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

William S. Bush, Bin Zhu, Angeline S. Andrew, 2017, Nature Genetics.

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer.

Francesmary Modugno, Honglin Song, Danielle Shadforth, 2007, Cancer research.

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

Peter Devilee, Alfons Meindl, Lesley McGuffog, 2010, Breast Cancer Research.

Polymorphism in the GALNT1 Gene and Epithelial Ovarian Cancer in Non-Hispanic White Women: The Ovarian Cancer Association Consortium

Hannah Yang, Shan Wang-Gohrke, Honglin Song, 2010, Cancer Epidemiology, Biomarkers & Prevention.

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.

Joshy George, Keitaro Matsuo, Ignace Vergote, 2014, Journal of the National Cancer Institute.

Abstract 162: DNA methylome in familial breast cancer identifies distinct profiles defined by mutation status

Peter T. Simpson, Georgia Chenevix-Trench, Kum Kum Khanna, 2010 .

Variation in the RAD51 gene and familial breast cancer

Georgia Chenevix-Trench, Graham J Mann, A. Spurdle, 2006, Breast Cancer Research.

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

Mads Thomassen, Nina Ditsch, Muhammad Usman Rashid, 2015, JAMA.

Gene-panel sequencing and the prediction of breast-cancer risk.

Nazneen Rahman, Peter Devilee, Alfons Meindl, 2015, The New England journal of medicine.

Association Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer

Gord Glendon, Lesley McGuffog, Daniel Barrowdale, 2012 .

The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers.

Rui Bi, Ronglai Shen, Nadeem Riaz, 2018, Journal of the National Cancer Institute.

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Brooke L. Fridley, Matthias W. Beckmann, Peter A. Fasching, 2013, Nature Genetics.

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium.

Michael Jones, Nazneen Rahman, Michael Bremer, 2011, Human molecular genetics.

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.

Julian Peto, Kyriaki Michailidou, Thomas Brüning, 2014, Human molecular genetics.

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

Patrick Neven, Peter Kraft, Nazneen Rahman, 2015 .

Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

Jennifer A. Doherty, Kexin Chen, Christopher I. Amos, 2019, Gynecologic oncology.

Investigation of gene‐environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors

Thomas Brüning, Kamila Czene, Ute Hamann, 2015, International journal of cancer.

Double-Strand Break Repair Gene Polymorphisms and Risk of Breast or Ovarian Cancer

John L Hopper, Georgia Chenevix-Trench, Graham G Giles, 2005, Cancer Epidemiology Biomarkers & Prevention.

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.

Wei Lu, Päivi Heikkilä, Peter Kraft, 2013, American journal of human genetics.

Genome-wide association studies identify four ER negative–specific breast cancer risk loci

Patrick Neven, Michael Jones, Wei Lu, 2013, Nature Genetics.

Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study.

Shan Wang-Gohrke, Honglin Song, Georgia Chenevix-Trench, 2009, Human molecular genetics.

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

Dong Liang, Brooke L. Fridley, Jennifer A. Doherty, 2015, Cancer Epidemiology, Biomarkers & Prevention.

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

Patrick Neven, Chiun-Sheng Huang, Julian Peto, 2014, Breast Cancer Research.

Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients

Brooke L. Fridley, M. Eileen Dolan, Soma Das, 2011, Clinical Cancer Research.

ESR1/SYNE1 Polymorphism and Invasive Epithelial Ovarian Cancer Risk: An Ovarian Cancer Association Consortium Study

Shan Wang-Gohrke, Honglin Song, Malcolm C Pike, 2010, Cancer Epidemiology, Biomarkers & Prevention.

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.

Mads Thomassen, Etienne Rouleau, Dieter Niederacher, 2010, Cancer research.

PALB2,CHEK2 and ATM rare variants and cancer risk: Data from COGS

Dong Liang, Jane E. Carpenter, Peter Kraft, 2016 .

Mutation analysis of RAD51L1 (RAD51B/REC2) in multiple-case, non-BRCA1/2 breast cancer families

Sue Healey, Georgia Chenevix-Trench, Kum Kum Khanna, 2011, Breast Cancer Research and Treatment.

Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Päivi Heikkilä, Mads Thomassen, Stephen Fox, 2011, Cancer Epidemiology, Biomarkers & Prevention.

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

Mads Thomassen, Stephen Fox, Dieter Niederacher, 2011, Breast Cancer Research.

Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer

Marc Vidal, Dieter Niederacher, Roderic Guigó, 2011, PLoS biology.

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

Olufunmilayo I. Olopade, Mads Thomassen, Dieter Niederacher, 2016, Breast Cancer Research.

BCoR-L1 variation and breast cancer

Georgia Chenevix-Trench, Kum Kum Khanna, Graham J Mann, 2007, Breast Cancer Research.

CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer

Georgia Chenevix-Trench, Felix Beck, G. Chenevix-Trench, 1998, Oncogene.

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.

Michael Jones, Julian Peto, Thomas Brüning, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

Wei Lu, Nina Ditsch, Julian Peto, 2013, American journal of human genetics.

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors

Georgia Chenevix-Trench, Ian G. Campbell, Ella R. Thompson, 2008, Breast Cancer Research and Treatment.

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

Matthias W. Beckmann, Peter A. Fasching, Nur Aishah Mohd Taib, 2014, Nature Communications.

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

Stephen Fox, Sue Healey, Brent Reynolds, 2010, Breast Cancer Research.

Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer.

Harvey Risch, Malcolm C Pike, Georgia Chenevix-Trench, 2013, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Genome-wide association analysis identifies three new breast cancer susceptibility loci

Michael Jones, Nazneen Rahman, Daniel J. Park, 2012, Nature Genetics.

Clinical classification of BRCA1 and BRCA2 DNA sequence variants: the value of cytokeratin profiles and evolutionary analysis--a report from the kConFab Investigators.

Sue Healey, John L Hopper, Georgia Chenevix-Trench, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.

Stefania Tommasi, Laura Cortesi, Mads Thomassen, 2019, Cancer research.

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk.

David V Conti, Honglin Song, Malcolm C Pike, 2011, Human molecular genetics.

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Dieter Niederacher, Ute Hamann, Alfons Meindl, 2008, American journal of human genetics.