H. Sakoh

发表

Discovery of novel arylpyrazole series as potent and selective opioid receptor-like 1 (ORL1) antagonists.

S. Ozaki, Y. Ishii, Yasushi Nagatomi, 2009, Bioorganic & medicinal chemistry letters.

Asymmetric Total Synthesis of Taxol\R

Toshihiro Nishimura, Isamu Shiina, T. Mukaiyama, 1999 .

Structure--activity relationships of 1beta-methyl-2-(5-phenylpyrrolidin-3-ylthio)carbapenems.

Hiroki Sato, S. Sakuraba, H. Morishima, 2002, Bioorganic & Medicinal Chemistry.

Synthesis of the side chain of a novel carbapenem via iodine-mediated oxidative cyclization of (1R)-N-(1-aryl-3-butenyl)acetamide.

H. Morishima, Koji Yamada, T. Hashihayata, 2002, Chemical & pharmaceutical bulletin.

Diastereoselective synthesis of (2R,4R)-2-aryl-4-hydroxypyrrolidine: preparation of the side chain of novel carbapenem.

S. Sakuraba, M. Hirose, H. Morishima, 2001, Chemical & pharmaceutical bulletin.

A NEW METHOD FOR THE SYNTHESIS OF BACCATIN III

Isamu Shiina, T. Mukaiyama, H. Iwadare, 1998 .

An Asymmetric Synthesis of the ABC Ring System of 8-Demethyltaxoids from Optically Active 8-Membered Ring Compound via Intramolecular Aldol and Pinacol Coupling Reactions

Toshihiro Nishimura, Isamu Shiina, T. Mukaiyama, 1997 .

Asymmetric Total Synthesis of Taxol

Isamu Shiina, T. Mukaiyama, H. Iwadare, 1999 .

Asymmetric Total Synthesis of TaxolR

Toshihiro Nishimura, Isamu Shiina, T. Mukaiyama, 1999 .

An Asymmetric Synthesis of the BC Ring System of 8-Epitaxoids by Way of Intramolecular Aldol and Successive Stereoselective Methylation Reactions

Toshihiro Nishimura, Isamu Shiina, T. Mukaiyama, 1996 .

Identification of an orally active opioid receptor-like 1 (ORL1) receptor antagonist 4-{3-[(2R)-2,3-dihydroxypropyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}-1-[(1S,3S,4R)-spiro[bicyclo[2.2.1]heptane-2,1'-cyclopropan]-3-ylmethyl]piperidine as clinical candidate.

Hisashi Ohta, Hiroshi Kawamoto, Satoshi Ozaki, 2009, Journal of medicinal chemistry.

IPC synthase as a useful target for antifungal drugs.

Koji Yamada, Y. Sugimoto, H. Sakoh, 2004, Current drug targets. Infectious disorders.

Identification of novel benzimidazole series of potent and selective ORL1 antagonists.

Y. Iwasawa, S. Ozaki, Y. Ishii, 2008, Bioorganic & medicinal chemistry letters.