O. O’Connell

发表

HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded

J. Luban, Shixia Wang, Shan Lu, 2017, Journal of Virology.

Targeted Delivery of Glucan Particle Encapsulated Gallium Nanoparticles Inhibits HIV Growth in Human Macrophages

P. Clapham, E. Soto, G. Ostroff, 2016, Journal of drug delivery.

The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies

S. Zolla-Pazner, D. Corti, P. Clapham, 2012, Retrovirology.

Ultradeep single-molecule real-time sequencing of HIV envelope reveals complete compartmentalization of highly macrophage-tropic R5 proviral variants in brain and CXCR4-using variants in immune and peripheral tissues

P. Clapham, R. Rose, D. Nolan, 2018, Journal of NeuroVirology.

Efficiency of Bridging-Sheet Recruitment Explains HIV-1 R5 Envelope Glycoprotein Sensitivity to Soluble CD4 and Macrophage Tropism

S. Zolla-Pazner, X. Kong, Shixia Wang, 2012, Journal of Virology.

Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue

P. Simmonds, J. Bell, P. Clapham, 2012, Retrovirology.

HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages

P. Clapham, P. Peters, M. Gonzalez-Perez, 2015, Retrovirology.

Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications

C. Harbison, P. Clapham, K. Luzuriaga, 2017, Journal of Virology.