Chao-Wu Yu

发表

Novel histone deacetylase inhibitors and embryo aggregation enhance cloned embryo development and ES cell derivation in pigs

J. Chern, J. Ju, C. Siriboon, 2018, PloS one.

Quinazolin-4-one derivatives as selective histone deacetylase-6 inhibitors for the treatment of Alzheimer's disease.

J. Chern, Ji-Wang Chern, Chao-Wu Yu, 2013, Journal of medicinal chemistry.

Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity.

H. Juan, J. Chern, Yi-Sheng Cheng, 2021, Bioorganic chemistry.

Efficient Microwave‐Assisted Pd‐Catalyzed Hydroxylation of Aryl Chlorides in the Presence of Carbonate.

J. Chern, G. Chen, Chao-Wu Yu, 2012 .

Efficient microwave-assisted Pd-catalyzed hydroxylation of aryl chlorides in the presence of carbonate.

J. Chern, G. Chen, Chao-Wu Yu, 2012, Organic letters.

Nickel-catalyzed cross coupling of cyclopropyl Grignard reagents with benzylic dithioacetals. Regioselective ring opening of cyclopropylcarbinyl organometallic intermediates. Novel synthesis of substituted dienes

T. Luh, D. Ng, Bi-Ling Chen, 1994 .

Quinazolin-2,4-dione-Based Hydroxamic Acids as Selective Histone Deacetylase-6 Inhibitors for Treatment of Non-Small Cell Lung Cancer.

J. Chern, Yi-Sheng Cheng, Hsing-Yi Lai, 2018, Journal of medicinal chemistry.

High‐selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma

J. Chern, L. Hsin, Jia-rong Liu, 2019, Biochemical pharmacology.

A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth

J. Chern, Jung-Hsin Lin, Ting-Rong Chern, 2015, Neuropharmacology.

A highly HDAC6-selective inhibitor acts as a fluorescent probe.

J. Chern, Yi-Sheng Cheng, Y. Ho, 2018, Organic & biomolecular chemistry.

Synthesis and structure-activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors.

J. Chern, Ling-mei Wang, Chiung-Hua Huang, 2010, Bioorganic & medicinal chemistry.

Discovery of HDAC6, HDAC8, and 6/8 Inhibitors and Development of Cell-Based Drug Screening Models for the Treatment of TGF-β-Induced Idiopathic Pulmonary Fibrosis.

J. Chern, Shau-Ping Lin, Shuei-Liong Lin, 2023, Journal of medicinal chemistry.

A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin‐induced apoptosis in castration‐resistant prostate cancer

J. Guh, L. Hsu, Wohn-Jenn Leu, 2024, The Prostate.

Discovery of novel anaplastic lymphoma kinase (ALK) and histone deacetylase (HDAC) dual inhibitors exhibiting antiproliferative activity against non-small cell lung cancer

Chao-Wu Yu, Tsung-Yu Yeh, Jia-Rong Liu, 2024, Journal of enzyme inhibition and medicinal chemistry.