E. K. Sinner

Evolution of Methods for the Study of Cobalamin-Dependent Radical SAM Enzymes

C. Townsend, Daniel R Marous, E. K. Sinner, 2021, ACS bio & med chem Au.

ThnL, a B12-dependent radical S-adenosylmethionine enzyme, catalyzes thioether bond formation in carbapenem biosynthesis

C. Townsend, Rongfeng Li, Daniel R Marous, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Methylations in complex carbapenem biosynthesis are catalyzed by a single cobalamin-dependent radical S-adenosylmethionine enzyme.

C. Townsend, Rongfeng Li, Daniel R Marous, 2019, Chemical communications.

Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis

C. Townsend, H. Knox, S. Booker, 2022, Nature.

Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis

C. Townsend, H. Knox, S. Booker, 2022, Nature.

Structural basis for carbapenam C-alkylation by TokK, a B12-dependent radical SAM enzyme

C. Townsend, H. Knox, S. Booker, 2021, bioRxiv.

SAR of non-hydrolysable analogs of pyridoxal 5'-phosphate against low molecular weight protein tyrosine phosphatase isoforms.

H. Jakubowski, E. McIntee, Samantha L Tinucci, 2020, Bioorganic & medicinal chemistry letters.