Nigel S Scrutton

发表

Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding. Relaxation kinetic studies with coenzyme analogues.

Gordon C K Roberts, Aldo Gutierrez, Andrew W Munro, 2003, European journal of biochemistry.

Multifragment DNA Assembly of Biochemical Pathways via Automated Ligase Cycling Reaction.

Neil Swainston, Eriko Takano, Nigel S Scrutton, 2018, Methods in enzymology.

Role of histidine 42 in ascorbate peroxidase. Kinetic analysis of the H42A and H42E variants.

Jaswir Basran, Nigel S Scrutton, Latesh Lad, 2002, European journal of biochemistry.

Rapid prototyping of microbial production strains for the biomanufacture of potential materials monomers

Neil Swainston, Pablo Carbonell, Sandra Taylor, 2020, Metabolic engineering.

Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli.

Neil Swainston, Rainer Breitling, Pablo Carbonell, 2019, ACS synthetic biology.

In silico design and automated learning to boost next-generation smart biomanufacturing

Eriko Takano, Pablo Carbonell, Nigel S Scrutton, 2020, Synthetic biology.

SelProm: A Queryable and Predictive Expression Vector Selection Tool for Escherichia coli.

Rainer Breitling, Pablo Carbonell, Sandra Taylor, 2019, ACS synthetic biology.

A Toolbox for Diverse Oxyfunctionalisation of Monoterpenes

Eriko Takano, Maria Vinaixa, Nigel S Scrutton, 2018, Scientific Reports.

An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

Carole Goble, Neil Swainston, Rainer Breitling, 2018, Communications Biology.

biochem4j: Integrated and extensible biochemical knowledge through graph databases

Sophia Ananiadou, Pablo Carbonell, Alan R. Williams, 2017, PloS one.

Building a global alliance of biofoundries

Douglas C. Friedman, Huimin Zhao, Filippo Menolascina, 2019, Nature Communications.

Good vibrations in enzyme-catalysed reactions.

Nigel S Scrutton, N. Scrutton, S. Hay, 2012, Nature chemistry.

What are the signatures of tunnelling in enzyme-catalysed reactions?

Nigel S Scrutton, N. Scrutton, L. Johannissen, 2019, Faraday discussions.

Systematic methodology for the development of biocatalytic hydrogen-borrowing cascades: application to the synthesis of chiral α-substituted carboxylic acids from α-substituted α,β-unsaturated aldehydes.

Nigel S Scrutton, Nicholas J Turner, N. Scrutton, 2015, Organic & biomolecular chemistry.

Synthetic biology for fibers, adhesives, and active camouflage materials in protection and aerospace

Rainer Breitling, Eriko Takano, William Finnigan, 2019, MRS Communications.

Engineering Escherichia coli towards de novo production of gatekeeper (2S)-flavanones: naringenin, pinocembrin, eriodictyol and homoeriodictyol

Andrew Currin, Rainer Breitling, Pablo Carbonell, 2020, Synthetic biology.

Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli.

Eriko Takano, Nigel S Scrutton, Antonios Lygidakis, 2015, ACS synthetic biology.

Continuous two-phase flow miniaturised bioreactor for monitoring anaerobic biocatalysis by pentaerythritol tetranitrate reductase.

Stephan Mohr, Nigel S Scrutton, Peter R Fielden, 2010, Lab on a chip.

A microbial platform for renewable propane synthesis based on a fermentative butanol pathway

Patrik R. Jones, Nigel S Scrutton, David Leys, 2015, Biotechnology for Biofuels.

Incorporation of hydrostatic pressure into models of hydrogen tunneling highlights a role for pressure-modulated promoting vibrations.

Nigel S Scrutton, N. Scrutton, S. Hay, 2008, Biochemistry.

Atomic Description of an Enzyme Reaction Dominated by Proton Tunneling

Adrian J Mulholland, Kara E Ranaghan, Jaswir Basran, 2006, Science.

Kinetic isotope effects and ligand binding in PQQ-dependent methanol dehydrogenase.

Nigel S Scrutton, Michael J Sutcliffe, M. Sutcliffe, 2005, The Biochemical journal.

A new conceptual framework for enzyme catalysis. Hydrogen tunnelling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes.

Nigel S Scrutton, Michael J Sutcliffe, M. Sutcliffe, 2002, European journal of biochemistry.

Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis

Nigel S Scrutton, Nicholas J Turner, Mark S Dunstan, 2017, Nature chemical biology.

Quantum catalysis in enzymes: beyond the transition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005

Nigel S Scrutton, Michael J Sutcliffe, P Leslie Dutton, 2006, Journal of The Royal Society Interface.

Production of Propane and Other Short-Chain Alkanes by Structure-Based Engineering of Ligand Specificity in Aldehyde-Deformylating Oxygenase

Nigel S Scrutton, David Leys, N. Scrutton, 2013, Chembiochem : a European journal of chemical biology.

Barrier compression and its contribution to both classical and quantum mechanical aspects of enzyme catalysis.

Nigel S Scrutton, Michael J Sutcliffe, M. Sutcliffe, 2010, Biophysical journal.

Relating localized protein motions to the reaction coordinate in coenzyme B12‐dependent enzymes

Nigel S Scrutton, N. Scrutton, Alex R. Jones, 2013, The FEBS journal.

New developments in 'ene'-reductase catalysed biological hydrogenations.

Nigel S Scrutton, N. Scrutton, H. Toogood, 2014, Current opinion in chemical biology.

Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins

Nigel S Scrutton, S. Antonyuk, S. Hasnain, 2011, Proceedings of the National Academy of Sciences.

How does pressure affect barrier compression and isotope effects in an enzymatic hydrogen tunneling reaction?

Nigel S Scrutton, Michael J Sutcliffe, M. Sutcliffe, 2011, Angewandte Chemie.

Direct analysis of donor-acceptor distance and relationship to isotope effects and the force constant for barrier compression in enzymatic H-tunneling reactions.

Nigel S Scrutton, Michael J Sutcliffe, M. Sutcliffe, 2010, Journal of the American Chemical Society.