Tomoharu Tsukada

Novel protein kinase cAMP-Activated Catalytic Subunit Alpha (PRKACA) inhibitor shows anti-tumor activity in a fibrolamellar hepatocellular carcinoma model.

O. Ubukata, S. Iwasaki, Akiko Toyota, 2022, Biochemical and biophysical research communications.

Formal total synthesis of altohyrtin C (spongistatin 2). Part 2: Construction of fully elaborated ABCD and EF fragments

Taisaku Tanaka, M. Nakata, N. Kanoh, 2003 .

Discovery of DS-6930, a potent selective PPARγ modulator. Part I: Lead identification.

Hideki Yamamoto, J. Ohsumi, N. Watanabe, 2018, Bioorganic & medicinal chemistry.

Discovery of DS-6930, a potent selective PPARγ modulator. Part II: Lead optimization.

Hideki Yamamoto, J. Ohsumi, N. Watanabe, 2018, Bioorganic & medicinal chemistry.

Formal total synthesis of altohyrtin C (spongistatin 2). Part 1: Aldol approach to unite AB and CD spiroacetals

M. Nakata, N. Kanoh, Takeshi Terauchi, 2003 .

A prodrug approach towards the development of tricyclic-based FBPase inhibitors.

A. Okuno, Mizuki Takahashi, K. Tamaki, 2010, Bioorganic & medicinal chemistry letters.

Discovery of potent and orally active tricyclic-based FBPase inhibitors.

A. Okuno, Mizuki Takahashi, T. Nishi, 2010, Bioorganic & medicinal chemistry.

Structure-based drug design of tricyclic 8H-indeno[1,2-d][1,3]thiazoles as potent FBPase inhibitors.

Mizuki Takahashi, T. Nishi, Takahiro Yamane, 2010, Bioorganic & medicinal chemistry letters.

Synthesis, SAR, and X-ray structure of tricyclic compounds as potent FBPase inhibitors.

Mizuki Takahashi, T. Nishi, Takahiro Yamane, 2009, Bioorganic & medicinal chemistry letters.