Kailee Leinonen-Wright

Caspase-2 mRNA levels are not elevated in mild cognitive impairment, Alzheimer’s disease, Huntington’s disease, or Lewy Body dementia

R. Petersen, K. Ashe, Lisa J. Kemper, 2022, PloS one.

A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

K. Ashe, C. Keene, Benjamin R. Smith, 2019, Acta Neuropathologica Communications.

Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy.

K. Ashe, M. Walters, D. Liao, 2022, ACS chemical neuroscience.

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

R. Petersen, D. Knopman, K. Ashe, 2020, Scientific Reports.

Developmental Pathogenicity of 4-Repeat Human Tau Is Lost with the P301L Mutation in Genetically Matched Tau-Transgenic Mice

K. Vossel, K. Ashe, W. Xia, 2020, The Journal of Neuroscience.

A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

K. Ashe, C. Keene, Benjamin R. Smith, 2019, Acta Neuropathologica Communications.

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

R. Petersen, D. Knopman, K. Ashe, 2020, Scientific Reports.

Blocking Site-Specific Cleavage of Human Tau Delays Progression of Disease-Related Phenotypes in Genetically Matched Tau-Transgenic Mice Modeling Frontotemporal Dementia

K. Ashe, C. Forster, P. Liu, 2022, The Journal of Neuroscience.