A. Otto-Bruc

发表

Translation of in vitro cannabinoid 1 receptor agonist activity to in vivo pharmacodynamic endpoints.

Asser Bassyouni, S. Jenkinson, P. Butler, 2020, Journal of pharmacological and toxicological methods.

Modulation of the GTPase activity of transducin. Kinetic studies of reconstituted systems.

B. Antonny, T. Vuong, A. Otto-Bruc, 1994, Biochemistry.

Tryptophan W207 in transducin T alpha is the fluorescence sensor of the G protein activation switch and is involved in the effector binding.

P. Chardin, E. Faurobert, M. Chabre, 1993, The EMBO journal.

Interaction between the retinal cyclic GMP phosphodiesterase inhibitor and transducin. Kinetics and affinity studies.

B. Antonny, P. Chardin, M. Chabre, 1993, Biochemistry.

GTP hydrolysis by purified alpha-subunit of transducin and its complex with the cyclic GMP phosphodiesterase inhibitor.

B. Antonny, B Antonny, A Otto-Bruc, 1993, Biochemistry.

Use of Broad Biological Profiling as a Relevant Descriptor to Describe and Differentiate Compounds: Structure–In Vitro (Pharmacology–ADME)–In Vivo (Safety) Relationships

Jonathan S. Mason, Jacques Migeon, J. Mason, 2008 .

Incorporation of In Vitro Techniques for Botanicals Dietary Supplement Safety Assessment - Towards evaluation of Developmental and Reproductive Toxicity (DART).

G. Daston, J. Naciff, C. Mahony, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Phosphorylation of photolyzed rhodopsin is calcium-insensitive in retina permeabilized by alpha-toxin.

K. Palczewski, R. Fariss, J. P. Van Hooser, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Guanylate-cyclase-inhibitory protein is a frog retinal Ca2+-binding protein related to mammalian guanylate-cyclase-activating proteins.

A. Milam, K. Palczewski, F. Haeseleer, 1998, European Journal of Biochemistry.

Localization of guanylate cyclase-activating protein 2 in mammalian retinas.

A. Milam, K. Palczewski, F. Haeseleer, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Dissociation of GDP Dissociation Inhibitor and Membrane Translocation Are Required for Efficient Activation of Rac by the Dbl Homology-Pleckstrin Homology Region of Tiam*

Bruno Antonny, B. Antonny, K. Robbe, 2003, The Journal of Biological Chemistry.

Functional reconstitution of photoreceptor guanylate cyclase with native and mutant forms of guanylate cyclase-activating protein 1.

K. Palczewski, P. Hargrave, W. Baehr, 1997, Biochemistry.

Calcium-Sensitive Particulate Guanylyl Cyclase as a Modulator of cAMP in Olfactory Receptor Neurons

K. Palczewski, G. Ronnett, C. Moon, 1998, The Journal of Neuroscience.

Conformational Changes in Guanylyl Cyclase-activating Protein 1 (GCAP1) and Its Tryptophan Mutants as a Function of Calcium Concentration*

C. Verlinde, K. Palczewski, W. Baehr, 1999, The Journal of Biological Chemistry.

[16] Use of α-toxin-permeabilized photoreceptors in in vitro phototransduction studies

R. Fariss, A. Otto-Bruc, J. V. Hooser, 2000 .

Construction of a Homogeneous and Informative In vitro Profiling Database for Anticipating the Clinical Effects of Drugs

N. Froloff, V. Hamon, P. Dupuis, 2006 .

The determination of epigenetic target specificity and identification of epigenetics-related in vivo adverse drug reactions

Boryeu Mao, J. Migeon, A. Otto-Bruc, 2013 .