Jessica A Bush

NEW SYNTHESES OF α-AMINO-ε-GUANIDINO-n-CAPROIC ACID (HOMOARGININE) AND ITS POSSIBLE CONVERSION IN VIVO INTO LYSINE

C. M. Stevens, Jessica A Bush, 1950 .

Study of an RNA-Focused DNA-Encoded Library Informs Design of a Degrader of a r(CUG) Repeat Expansion.

M. Disney, A. Taghavi, H. Aikawa, 2022, Journal of the American Chemical Society.

Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTD.

Jonathan L Chen, L. Petrucelli, Ilyas Yildirim, 2020, ACS chemical biology.

A blood–brain penetrant RNA-targeted small molecule triggers elimination of r(G4C2)exp in c9ALS/FTD via the nuclear RNA exosome

Jessica L. Childs-Disney, L. Petrucelli, M. Disney, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models

Eric T. Wang, Jonathan L Chen, Jessica L. Childs-Disney, 2021, Science Translational Medicine.

A Small Molecule Exploits Hidden Structural Features within the RNA Repeat Expansion That Causes c9ALS/FTD and Rescues Pathological Hallmarks.

L. Petrucelli, Ilyas Yildirim, M. Disney, 2021, ACS chemical neuroscience.