M. Niemeijer

发表

Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids

J. Ijzermans, M. Verstegen, L. J. van der Laan, 2021, Cellular and molecular gastroenterology and hepatology.

Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage.

B. Water, S. Wink, S. Hiemstra, 2017, Chemical research in toxicology.

In Vitro Three-Dimensional Liver Models for Nanomaterial DNA Damage Assessment.

M. J. Moné, B. van de Water, S. Doak, 2021, Small.

Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment.

Bob van de Water, Harry Vrieling, Giel Hendriks, 2014, Chemical research in toxicology.

From Fatty Hepatocytes to Impaired Bile Flow: Matching Model Systems for Liver Biology and Disease.

L. J. van der Laan, S. V. D. van de Graaf, Marije Niemeijer, 2020, Biochemical pharmacology.

Transcriptomic mapping of the inter-individual variability of cellular stress response activation in primary human hepatocytes

R. Paules, F. Bois, B. van de Water, 2021, bioRxiv.

ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

B. van de Water, Huan Yang, Marije Niemeijer, 2020, iScience.

Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages

Sylvia E. Le Dévédec, M. J. Moné, C. Verfaillie, 2021, Archives of Toxicology.

Utility of Extrapolating Human S1500+ Genes to the Whole Transcriptome: Tunicamycin Case Study

S. Auerbach, Ruchir R. Shah, R. Paules, 2020, Bioinformatics and biology insights.

Systems Microscopy Approaches in Unraveling and Predicting Drug-Induced Liver Injury (DILI)

B. Water, S. Wink, B. T. Braak, 2018 .

Model-based translation of DNA damage signaling dynamics across cell types

B. van de Water, H. Yang, S. L. Le Dévédec, 2022, PLoS Comput. Biol..

Assessing the transferability and reproducibility of 3D in vitro liver models from primary human multi-cellular microtissues to cell-line based HepG2 spheroids.

M. J. Moné, N. Jacobsen, B. van de Water, 2022, Toxicology in vitro : an international journal published in association with BIBRA.

Integration of temporal single cell cellular stress response activity with Logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury.

Sylvia E. Le Dévédec, J. Saez-Rodriguez, J. Hengstler, 2021, Biochemical pharmacology.

The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment

E. Guney, J. Saez-Rodriguez, L. Furlong, 2021, Archives of Toxicology.

Preclinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies

Neal C Burton, Julie Holder, Neal C. Burton, 2017, npj Regenerative Medicine.

The human hepatocyte TXG-MAPr: WGCNA transcriptomic modules to support mechanism-based risk assessment

E. Guney, J. Saez-Rodriguez, L. Furlong, 2021, bioRxiv.

Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes.

C. Verfaillie, B. van de Water, R. Boon, 2021, Toxicology in vitro : an international journal published in association with BIBRA.