Xiuguo Zhang

发表

Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones

T. Chou, S. Danishefsky, Rebecca M. Wilson, 2008, Proceedings of the National Academy of Sciences.

Potent DNA-directed alkylating agents: Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboxamide linker.

T. Chou, Te-Chang Lee, Amit Kumar, 2010, Bioorganic & medicinal chemistry.

Potent antitumor bifunctional DNA alkylating agents, synthesis and biological activities of 3a-aza-cyclopenta[a]indenes.

T. Chou, Te-Chang Lee, Pei-Chih Lee, 2009, Bioorganic & medicinal chemistry.

Novel DNA-directed alkylating agents: design, synthesis and potent antitumor effect of phenyl N-mustard-9-anilinoacridine conjugates via a carbamate or carbonate linker.

T. Tsai, T. Chou, Te-Chang Lee, 2009, Bioorganic & medicinal chemistry.

Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.

Yu-Tse Wu, T. Tsai, T. Chou, 2008, Bioorganic & medicinal chemistry.

Multifaceted cytoprotection by synthetic polyacetylenes inspired by the ginseng-derived natural product, panaxytriol

T. Chou, Xiaoguang Lei, J. H. Lee, 2011, Proceedings of the National Academy of Sciences.

Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents.

T. Chou, Te-Chang Lee, Pei-Chih Lee, 2011, Bioorganic & medicinal chemistry.

Synthesis and in vitro cytotoxicity of 9-anilinoacridines bearing N-mustard residue on both anilino and acridine rings.

T. Chou, R. Kakadiya, Ching-Huang Chen, 2009, European journal of medicinal chemistry.

Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: synthesis and biological activity.

T. Chou, Leroy F. Liu, Ching-Huang Chen, 2006, Journal of Medicinal Chemistry.

A Novel Aldol Condensation with 2-Methyl-4-pentenal and Its Application to an Improved Total Synthesis of Epothilone B.

K. Savin, T. Chou, A. Balog, 1998, Angewandte Chemie.

Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity.

Xiuguo Zhang, T. Chou, Leroy F. Liu, 2005, Bioorganic & medicinal chemistry.

Therapeutic cure against human tumor xenografts in nude mice by a microtubule stabilization agent, fludelone, via parenteral or oral route.

Xiuguo Zhang, T. Chou, S. Danishefsky, 2005, Cancer research.

Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.

K. Savin, J. Bertino, A. Balog, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

K. Savin, T. Chou, S. Kuduk, 1998, Proceedings of the National Academy of Sciences of the United States of America.