Wen‐chi Hsiao

发表

Discovery of novel N-β-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.

C. Chen, Y. Chao, Chieh-Jui Hsieh, 2011, Journal of medicinal chemistry.

4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy.

Y. Chao, Su-Ying Wu, Jen‐Shin Song, 2018, Bioorganic chemistry.

Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy.

Yi-Hui Peng, Y. Chao, Su-Ying Wu, 2016, Journal of medicinal chemistry.

Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening.

Yi-Hui Peng, A. Yueh, J. Hsu, 2015, Journal of medicinal chemistry.

Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design.

Yi-Hui Peng, Su-Ying Wu, Jen‐Shin Song, 2021, European journal of medicinal chemistry.

Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1.

Su-Ying Wu, Jian-Sung Wu, Yi-Hui Peng, 2016, Journal of medicinal chemistry.

Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors

Kak‐Shan Shia, M. Hung, R S Vijayakumar, 2012, International Journal of Obesity.

Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors.

Y. Chao, Su-Ying Wu, Jian-Sung Wu, 2014, Bioorganic & medicinal chemistry letters.

Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists.

Jen‐Shin Song, Kun-Yi Hsin, Kak‐Shan Shia, 2022, Bioorganic chemistry.

Discovery of 1‐(2,4‐Dichlorophenyl)‐4‐ethyl‐5‐(5‐(2‐(4‐(trifluoromethyl)phenyl)ethynyl)thiophen‐2‐yl)‐N‐(piperidin‐1‐yl)‐1H‐pyrazole‐3‐carboxamide as a Potential Peripheral Cannabinoid‐1 Receptor Inverse Agonist

Y. Chao, Jen‐Shin Song, T. Yeh, 2010, ChemMedChem.

Analysis of global methylation using a Zta-expressing nasopharyngeal carcinoma cell line.

H. Sun, Yao Chang, Chao-Ling Tung, 2011, Genomics.

A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis

Kak‐Shan Shia, M. Hung, Wenchi Hsiao, 2015, Diabetes, obesity & metabolism.

Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities.

Y. Chao, T. Yeh, Kak‐Shan Shia, 2010, Pharmacological research.