H. Chen

发表

Positive Charge at Position 549 Is Essential for Phosphatidylinositol 4,5-Bisphosphate-hydrolyzing but Not Phosphatidylinositol-hydrolyzing Activities of Human Phospholipase C δ1*

C. Lim, Y. Kuan, K. King, 1996, The Journal of Biological Chemistry.

Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing.

C. Walsh, H. Chen, Z. Suo, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Phosphinic derivatives as new dual enkephalin-degrading enzyme inhibitors: synthesis, biological properties, and antinociceptive activities.

P. Coric, B. Roques, H. Meudal, 2000, Journal of medicinal chemistry.

Aminophosphinic inhibitors as transition state analogues of enkephalin-degrading enzymes: a class of central analgesics.

M. Fournié-Zaluski, P. Coric, B. Roques, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Binding properties of a highly potent and selective iodinated aminopeptidase N inhibitor appropriate for radioautography

M. Fournié-Zaluski, B. Roques, N. Luciani, 2000, FEBS Letters.

Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis.

C. Walsh, B. Hubbard, M. Burkart, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines.

C. Walsh, D. Miller, B. Hubbard, 2001, Current opinion in chemical biology.

Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI.

C. Walsh, H. Chen, 2001, Chemistry & biology.

First discrete autoradiographic distribution of aminopeptidase N in various structures of rat brain and spinal cord using the selective iodinated inhibitor [125I]RB 129

M. Fournié-Zaluski, B. Roques, S. Parsadaniantz, 2001, Neuroscience.

Antiviral activities of methylated nordihydroguaiaretic acids. 2. Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor tetra-O-methyl-NDGA.

R. Park, Ru-chih C. Huang, Jiannong Li, 1998, Journal of medicinal chemistry.

Epothilone biosynthesis: assembly of the methylthiazolylcarboxy starter unit on the EpoB subunit.

C. Walsh, D. Cane, S. O’Connor, 2001, Chemistry & biology.

Long lasting antinociceptive properties of enkephalin degrading enzyme (NEP and APN) inhibitor prodrugs.

M. Fournié-Zaluski, B. Roques, F. Noble, 2001, Journal of medicinal chemistry.

Aminoacyl-S-enzyme intermediates in beta-hydroxylations and alpha,beta-desaturations of amino acids in peptide antibiotics.

C. Walsh, B. Hubbard, S. O’Connor, 2001, Biochemistry.

Type and location of fluorescent probes incorporated into the potent mu-opioid peptide [Dmt]DALDA affect potency, receptor selectivity and intrinsic efficacy.

P. Schiller, C. Lemieux, N. N. Chung, 2005, The journal of peptide research : official journal of the American Peptide Society.

Structure-activity relationships in a series of 5-[(2,5-dihydroxybenzyl)amino]salicylate inhibitors of EGF-receptor-associated tyrosine kinase: importance of additional hydrophobic aromatic interactions.

B. Roques, B. Tocqué, J. Le Pecq, 1994, Journal of medicinal chemistry.

Synthesis and structure-activity studies of a series of [(hydroxybenzyl)amino]salicylates as inhibitors of EGF receptor-associated tyrosine kinase activity.

B. Roques, B. Tocqué, R. Maroun, 1993, Journal of medicinal chemistry.

Synthesis and biological evaluation of a series of hydroxybenzylphenylamine derivatives as inhibitors of EGF receptor-associated tyrosine kinase activity.

B. Roques, B. Tocqué, C. Garbay, 1996, Anti-Cancer Drug Design.

The purification and characterization of a phospholipase A in hamster heart cytosol for the hydrolysis of phosphatidylcholine.

P. Choy, S. W. Tam, G. Arthur, 1987, The Journal of biological chemistry.