Kristen Wong

Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors.

J. Luengo, A. P. Graves, M. Pappalardi, 2019, ACS medicinal chemistry letters.

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Peter A. Jones, Philip J. Chapman, P. Grandi, 2021, Nature Cancer.

Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors.

Xiaodong Cheng, Xing Zhang, M. Pappalardi, 2022, Structure.

Abstract 2994: Discovery of selective, noncovalent small molecule inhibitors of DNMT1 as an alternative to traditional DNA hypomethylating agents

J. Briand, R. Prinjha, Mark Cockerill, 2018, Molecular and Cellular Biology / Genetics.

Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors.

Xiaodong Cheng, Xing Zhang, M. Pappalardi, 2022, Structure.