Radka Chaloupkova

发表

FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

David Baker, Jaroslav Bendl, Jan Brezovsky, 2015, PLoS Comput. Biol..

Expansion of Access Tunnels and Active‐Site Cavities Influence Activity of Haloalkane Dehalogenases in Organic Cosolvents

Jan Sykora, Jan Brezovsky, Zbynek Prokop, 2013, Chembiochem : a European journal of chemical biology.

Enzymatic Reaction Coupled with Flow-Injection Analysis with Charged Aerosol, Coulometric, or Amperometric Detection for Estimation of Contamination of the Environment by Pesticides

Vojtech Adam, Zbynek Prokop, Radka Chaloupkova, 2008 .

Different Structural Origins of the Enantioselectivity of Haloalkane Dehalogenases toward Linear β-Haloalkanes: Open-Solvated versus Occluded-Desolvated Active Sites.

Jan Brezovsky, Zbynek Prokop, David Bednar, 2017, Angewandte Chemie.

Organic co‐solvents affect activity, stability and enantioselectivity of haloalkane dehalogenases

Radka Chaloupkova, Jiri Damborsky, J. Damborský, 2013, Biotechnology journal.

Impact of the access tunnel engineering on catalysis is strictly ligand‐specific

Jan Brezovsky, Zbynek Prokop, Radka Chaloupkova, 2018, The FEBS journal.

Catalytic Cycle of Haloalkane Dehalogenases Toward Unnatural Substrates Explored by Computational Modeling

Jan Brezovsky, Zbynek Prokop, Radka Chaloupkova, 2017, J. Chem. Inf. Model..

Crystallographic analysis of 1,2,3-trichloropropane biodegradation by the haloalkane dehalogenase DhaA31.

Radka Chaloupkova, Jiri Damborsky, J. Damborský, 2014, Acta crystallographica. Section D, Biological crystallography.

Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.

Jan Brezovsky, Zbynek Prokop, Eva Sebestova, 2013, Angewandte Chemie.

Dynamics and hydration explain failed functional transformation in dehalogenase design.

Jan Sykora, Jan Brezovsky, Zbynek Prokop, 2014, Nature chemical biology.

Haloalkane dehalogenases: Biotechnological applications

Zbynek Prokop, Pavel Dvorak, Radka Chaloupkova, 2013, Biotechnology journal.

Pathways and mechanisms for product release in the engineered haloalkane dehalogenases explored using classical and random acceleration molecular dynamics simulations.

Zbynek Prokop, Pavel Dvorak, Radka Chaloupkova, 2009, Journal of molecular biology.

Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering.

Yuji Nagata, Jan Brezovsky, Zbynek Prokop, 2010, Angewandte Chemie.

Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate.

Yuji Nagata, Michal Otyepka, Zbynek Prokop, 2009, Nature chemical biology.