K. Miyake

发表

Enantioselective pharmacokinetics of homochlorcyclizine II: disposition and metabolism of (+)-, (−)- and racemic homochlorcyclizine after oral administration to man

M. Nishikata, T. Arita, K. Iseki, 2005, European Journal of Clinical Pharmacology.

Solubility and mass and nuclear magnetic resonance spectroscopic studies on interaction of cyclosporin A with dimethyl-alpha- and -beta-cyclodextrins in aqueous solution.

F. Hirayama, K. Uekama, K. Miyake, 1999, Journal of pharmaceutical sciences.

Improvement of Solubility and Oral Bioavailability of Rutin by Complexation with 2-Hydroxypropyl-β-cyclodextrin

F. Hirayama, K. Uekama, H. Arima, 2000, Pharmaceutical development and technology.

Characterization of itraconazole/2-hydroxypropyl-beta-cyclodextrin inclusion complex in aqueous propylene glycol solution.

F. Hirayama, K. Uekama, H. Arima, 1999, International journal of pharmaceutics.

Comparative studies of the enhancing effects of cyclodextrins on the solubility and oral bioavailability of tacrolimus in rats.

F. Hirayama, K. Uekama, H. Arima, 2001, Journal of pharmaceutical sciences.

Characterization of Itraconazole / 2-Hydroxypropyl-ß-Cyclodextrin Inclusion Complex in Aqueous Solution

A. Kondo, F. Hirayama, K. Uekama, 1999 .

Gastrointestinal absorption of sulfaguanidine in neonatal and adult rats.

M. Nishikata, N. Mizuno, K. Miyake, 1986, Journal of pharmacobio-dynamics.

Comparison of the pharmacokinetics of five beta-lactam antibiotics between neonatal and adult rats.

M. Nishikata, N. Mizuno, K. Miyake, 1990, Developmental pharmacology and therapeutics.

Enhanced absorption of cyclosporin A by complexation with dimethyl-beta-cyclodextrin in bile duct-cannulated and -noncannulated rats.

F. Hirayama, K. Uekama, H. Arima, 1999, Biological & pharmaceutical bulletin.

Enantioselective pharmacokinetics of homochlorcyclizine. III. Simultaneous determination of (+)- and (-)- homochlorcyclizine in human urine by high-performance liquid chromatography.

M. Nishikata, T. Arita, K. Iseki, 1993, Journal of Chromatography A.

Method for optical resolution of racemic homochlorcyclizine and comparison of optical isomers in antihistamine activity and pharmacokinetics.

M. Nishikata, T. Arita, K. Iseki, 1992, Chemical & pharmaceutical bulletin.

Effect of first-pass metabolism on enantioselective pharmacokinetics after oral administration of (+)-, (-)- and racemic homochlorcyclizine to rats.

M. Nishikata, T. Arita, K. Iseki, 1994, Biological & pharmaceutical bulletin.