T. Tsuchiya

发表

A new microbial metabolite phosphoramidon (Isolation and structure)

H. Umezawa, K. Tatsuta, S. Umezawa, 1972 .

RECENT CHEMICAL STUDIES OF BIOACTIVE MICROBIAL PRODUCTS : GENETICS , ACTIVE STRUCTURES , DEVELOPMENT OF EFFECTIVE AGENTS WITH POTENTIAL USEFULNESS

Y. Okazaki, S. Umezawa, T. Tsuchiya, 2022 .

Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide.

A. Tanaka, M. Hamada, H. Umezawa, 1984, The Journal of antibiotics.

Chemistry and developments of fluorinated carbohydrates.

T. Tsuchiya, 1990, Advances in carbohydrate chemistry and biochemistry.

Synthesis of 1-N-[(2S,4S)- and (2S,4R)-5-amino-4-fluoro-2-hydroxypentanoyl]dibekacins (study on structure-toxicity relationships).

Y. Takahashi, J. Kohno, T. Tsuchiya, 1998, Carbohydrate research.

Synthesis of (14R)- and (14S)-14-De(hydroxymethyl)-14-hydroxymycaminosyl Tylonolides

H. Umezawa, S. Sakamoto, S. Umezawa, 1987 .

Syntheses of 23-C-substituted derivatives of mycaminosyl tylonolide.

M. Hamada, H. Umezawa, S. Sakamoto, 1986, The Journal of antibiotics.

N-Substituted derivatives of 23-amino-4',23-dideoxymycaminosyl tylonolide. Synthesis and antibacterial activity.

A. Tanaka, M. Hamada, H. Umezawa, 1985, The Journal of antibiotics.

Syntheses of 23-dialkylamino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide effective against gram-negative bacteria.

A. Tanaka, M. Hamada, H. Umezawa, 1982, The Journal of antibiotics.

Syntheses of derivatives of 4'-deoxymycaminosyl tylonolide and mycaminosyl tylonolide modified AT C-23.

A. Tanaka, M. Hamada, H. Umezawa, 1981, The Journal of antibiotics.

Synthesis of antitumor-active 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone.

H. Umezawa, S. Umezawa, Y. Takagi, 1987, Carbohydrate research.

Synthesis of α,α-, α,β-, and β,β-(dimaltoside)s of ethane-1,2-diol, propane-1,3-diol, and butane-1,4-diol: A proposal for an initial adhesion mode

T. Tsuchiya, M. Tsuzuki, 1998 .

Reactions at Oxygen Atoms

T. Tsuchiya, 2001 .

Studies on Aminosugars. XXIV. The Facile Elimination of the Derivatives of a Pyranosid-4-ulose

S. Umezawa, T. Tsuchiya, K. Suo, 1970 .

Letter: Argvalin, a new microbial metabolite: isolation and structure.

K. Tatsuta, M. Yamashita, K. Fujimoto, 1973, The Journal of antibiotics.

REVISED STRUCTURE FOR ARGLEGIN

H. Naganawa, H. Umezawa, K. Tatsuta, 1972 .

Arglecin, a new microbial metabolite isolation and chemical structure.

H. Umezawa, K. Tatsuta, T. Someno, 1971, The Journal of antibiotics.

The structure of arglecin, a new metabolite of streptomyces

H. Naganawa, H. Umezawa, K. Tatsuta, 1971 .

Preparative, thin-layer chromatography in carbohydrate chemistry

D. Horton, T. Tsuchiya, 1967 .

Studies of Aminosugars. XII. The Absolute Structure of Kanamycin as Determined by a Copper Complex Method

K. Tatsuta, S. Umezawa, T. Tsuchiya, 1966 .

A CONVENIENT METHOD FOR DEUTERATION AT THE ALPHA POSITION OF AN OXO GROUP IN CARBOHYDRATES

A. Nemr, T. Tsuchiya, 1998 .

Deoxygenation of sugar trifluoromethanesulfonates by sodium metal in liquid ammonia and by photolysis

S. Umezawa, T. Tsuchiya, F. Nakamura, 1979 .

Photochemical Reaction at 3-O-Functional Group of Methyl 4,6-O-CycIohexylidene-2-deoxy-2-methoxycarbonylamino-α-D-glucopyranoside Derivatives

T. Kishi, S. Umezawa, T. Tsuchiya, 1979 .

Studies on Aminosugars. XXXI. Synthesis of 3,4-Dideoxy-3-enosides and the Corresponding 3,4-Dideoxysugars

Y. Okazaki, S. Umezawa, T. Tsuchiya, 1972 .

Synthesis and reactions of unsaturated sugars

D. Horton, T. Tsuchiya, E. L. Albano, 1966 .

Syntheses of methyl 6-deoxy-6-hydroxyamino-α-d-glucopyranoside, 6′-N-hydroxykanamycin A, and 6′-N-hydroxydibekacin

T. Torii, Yukiko Suzuki, S. Umezawa, 1985 .

Syntheses of 1-Epikanamycin A and Its 1-N-[(S)-4-Amino-2-hydroxybutyryl] Derivative

H. Umezawa, Yoshiaki Takahashi, Yukiko Suzuki, 1983 .

SYNTHESES AND ANTITUMOR ACTIVITIES OF 7-O-(2, 6-DIDEOXY-2-FLUORO-α-L-TALOPYRANOSYL)-DAUNOMYCINONE AND -ADRIAMYCINONE

T. Takeuchi, H. Umezawa, S. Umezawa, 1986 .

Syntheses of 2-Amino-2,3-dideoxy-L- and -D-Ribohexose by Utilizing an O→N Acetyl Migration

S. Umezawa, T. Yamasaki, T. Tsuchiya, 1976 .

Study on fluorination of 2,3-dideoxy-2,3-(N-tosylepimino)-alpha-D-allopyranosides, and synthesis of 3'-deoxy-3'-fluorokanamycin B and 3',4'-dideoxy-3'-fluorokanamycin B.

T. Ohgi, Y. Kobayashi, T. Tsuchiya, 1992, Carbohydrate research.

Reaction of methyl 2-deoxy-3-o-sulfonyl-2-p-toluenesulfonamido-α- and β-d-glucopyranoside derivatives with halide ions

Yoshiaki Takahashi, T. Miyake, S. Umezawa, 1981 .

Studies on Aminosugars. XXVIII. Synthesis of β-L-Idopyranosides through the Corresponding 5-Enopyranosides

D. Ikeda, S. Umezawa, T. Tsuchiya, 1971 .

A synthesis of dihydrostreptomycin.

S. Umezawa, T. Yamasaki, T. Tsuchiya, 1978, The Journal of antibiotics.

Synthesis of kanamycin A analogs containing a 6-amino-6-deoxyglycofuranose moiety.

Y. Kobayashi, K. Ohtsuki, T. Ohgami, 2000, Carbohydrate research.

A synthetic study of methyl 3-deoxy-3-fluoro-α-d-glucopyranosides from methyl 2,3-anhydro-α-d-allopyranosides, and synthesis of 3′-deoxy-3′-fluorokanamycin A and 3′-chloro-3′-deoxykanamycin A

Koichi Tanaka, Yoshihiko Kobayashi, E. Umemura, 1992 .

Reactions of Benzyl 2-Benzyloxycarbonylamino-2-deoxy-3-O-mesyl-α-D-gluco- and -α-D-allopyranoside Derivative with Iodide

H. Sano, S. Iimura, S. Umezawa, 1978 .

Studies of Aminosugars. XI. Configurational Studies of Aminosugar Glycosides and Aminocyclitols by a Copper Complex Method

K. Tatsuta, S. Umezawa, T. Tsuchiya, 1966 .

KD16-U1, a new metabolite of Streptomyces: isolation and structural studies.

H. Naganawa, H. Umezawa, K. Tatsuta, 1974, The Journal of antibiotics.

Studies on Aminosugars. XXX. The Synthesis of 3′-Deoxykanamycin

H. Umezawa, Kohei Watanabe, Y. Nishimura, 1972 .

Studies on the Formation of Deoxy Sugars by Detosyloxylation with Lithium Aluminum Hydride

S. Umezawa, T. Tsuchiya, H. Hineno, 1970 .

Synthesis of 6"-chloro-6"-deoxyamikacin and some its analogs.

K. Tanaka, E. Umemura, S. Umezawa, 1990, The Journal of antibiotics.

Studies on Glycosylation of erythro-β-Hydroxy-L-histidine. A Key Step of Bleomycin Total Synthesis

H. Umezawa, T. Miyake, S. Umezawa, 1986 .

Acid-catalyzed degradation of 2,3-unsaturated sugar

D. Horton, T. Tsuchiya, 1966 .

Transformation of Dihydrostreptomycin into 3″-Deoxydihydrostreptomycin

H. Umezawa, T. Usui, S. Umezawa, 1981 .

Synthesis of 2′,3′-Dideoxy-2′-Fluorokanamycin A

H. Umezawa, Yoshiaki Takahashi, S. Umezawa, 1985 .

Synthesis of 3-Deoxy-5-O-mycaminosyltylonolide and 3-Deoxy-5-O-(4-deoxymycaminosyl)tylonolide

M. Orita, S. Kageyama, S. Umezawa, 1992 .

Synthesis of kanamycin A analogs containing 6-amino-3-oxa-2,3,4,6-tetradeoxy-D- and -L-glycero-hexopyranose.

T. Tsuchiya, R. Kuwahara, 1996, Carbohydrate research.

Studies of Aminosugars. XIV. Syntheses of 6,6′-Diamino-6,6′-dideoxymaltosylamine, 1′,6,6′-Triamino-,1′,6,6′-trideoxysucrose and 6,6′-Diamino-6,6′-dideoxytrehalose

K. Tatsuta, S. Umezawa, T. Tsuchiya, 1967 .

The Formation of Methyl Methanethiolsulfonate, an Antibacterial Substance, from Dimethylsulfoxide

S. Umezawa, T. Tsuchiya, S. Iriyama, 1964 .

Synthesis of 4'-deoxymycaminosyl tylonolide.

H. Umezawa, S. Umezawa, A. Tanaka, 1981, The Journal of antibiotics.

Synthesis of 3"-epi-dihydrostreptomycin active against resistant bacteria.

H. Umezawa, S. Sakamoto, S. Umezawa, 1976, The Journal of antibiotics.

3',4'-dideoxy-kanamycin B active against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa.

H. Umezawa, Y. Okazaki, S. Umezawa, 1971, The Journal of antibiotics.

Syntheses of 3-fluoro-, 3-epi-3-fluoro-, and 3,3-difluoro-3-de(methoxy)sporaricin A☆

T. Torii, Yukiko Suzuki, S. Umezawa, 1983 .

Syntheses of 3-O-substituted 3-O-demethylsporaricins A

Takashi Yamaguchi, T. Mori, T. Tsuchiya, 1982 .

Synthesis of 5-deoxy-5-fluorosporaricin A

T. Torii, S. Umezawa, T. Tsuchiya, 1983 .

Synthesis of 3'-deoxy-3'-fluorokanamycins A and B active against resistant bacteria.

Y. Takahashi, H. Umezawa, S. Umezawa, 1985, The Journal of antibiotics.

The synthesis of kanamycin-6"-uronic acid, its ester and amide.

K. Tatsuta, S. Umezawa, T. Tsuchiya, 1970, The Journal of antibiotics.

Studies on Aminosugars. XXVI. A New Method for the Simultaneous Protection of Amino and Hydroxyl Groups in Aminosugars and Aminocyclitols

S. Umezawa, Y. Takagi, T. Tsuchiya, 1971 .

Syntheses of 1-N-(2-aminoethoxycarbonyl)kanamycin A and 1-N-(3-aminopropoxycarbonyl)kanamycin A.

M. Hamada, H. Umezawa, S. Umezawa, 1981, Journal of antibiotics (Tokyo. 1968).

Studies on Aminosugars. XXXIII. Syntheses of 4-Azido-2,3,6-tri- O -benzyl-4-deoxy- and 6-Azido-2,3,4-tri- O -benzyl-6-deoxy-α- D -glucopyranosyl Chloride

S. Umezawa, Y. Takagi, T. Tsuchiya, 1973 .

Synthesis of 6-Amino-6-deoxy-L-idopyranosides

T. Torii, S. Umezawa, T. Tsuchiya, 1986 .

Syntheses and antitumor activities of 7-O-(6-deoxy-2-O-methyl-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone.

T. Takeuchi, K. Komuro, C. Nosaka, 1989, The Journal of antibiotics.

Synthesis of 3'-deoxykanamycin effective against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa.

H. Umezawa, Y. Nishimura, S. Umezawa, 1971, The Journal of antibiotics.

Syntheses of Lividomycin B Analogues, 5-O-[3-O-(6-Amino-6-deoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]-3′-deoxyparomamine and ribofuranosyl]-3′-deoxyparomamine

T. Torii, S. Umezawa, T. Tsuchiya, 1982 .

Total Synthesis and Chemical Modification of the Aminoglycoside Antibiotics

S. Umezawa, T. Tsuchiya, 1982 .

Synthesis of 1-N-[(S)-4-amino-2-hydroxybutyryl]-3'-deoxyribostamycin (3'-deoxybutirosin B).

H. Umezawa, D. Ikeda, S. Umezawa, 1976 .

Synthesis of 3'-deoxybutirosin B.

H. Umezawa, D. Ikeda, S. Umezawa, 1975, The Journal of antibiotics.

Synthesis of Butirosin B and Its 3′,4′-Dideoxy Derivative

H. Umezawa, D. Ikeda, S. Umezawa, 1974 .

Total synthesis of dihydrostreptomycin.

H. Sano, Y. Takahashi, S. Umezawa, 1974, Journal of the American Chemical Society.

Synthesis of butirosin B.

H. Umezawa, D. Ikeda, S. Umezawa, 1972, The Journal of antibiotics.

Studies on Aminosugars. XXV. The Synthesis of Position Isomers of α- D -Glucopyranosyl-2-deoxystreptamine

Y. Nishimura, S. Umezawa, T. Tsuchiya, 1970 .

A New Method for the Protection of trans-Diequatorial Amino and Hydroxyl Groups in Aminosugars and Aminocyclitols

S. Umezawa, Y. Takagi, T. Tsuchiya, 1970 .

Synthesis of 5-O-(4-deoxy-4-fluoro-β-D-mycaminosyl)tylonolide

H. Umezawa, S. Kageyama, S. Umezawa, 1987 .

α-Hydrogen Elimination in Some Carbohydrate Triflates.

A. Nemr, T. Tsuchiya, 1995 .

Total synthesis of the disaccharide of bleomycin, 2-0-(α-D-mannopyranosyl)-L-gulopyranose

T. Takita, H. Umezawa, T. Miyake, 1981 .

Synthesis of 2-Amino-2,3-dideoxy-L-ribohexose

H. Sano, S. Umezawa, T. Tsuchiya, 1976 .

Synthesis of 3-O-acetyl-2,6-diazido-4-O-benzyl-2,6-dideoxy-l-idopyranosyl chloride, a glycosyl halide for the synthesis of neomycin B

T. Usui, S. Umezawa, Y. Takagi, 1984 .

Studies on Aminosugars. XXIX. The Synthesis of 3′-O-Methylkanamycin

H. Umezawa, S. Umezawa, T. Tsuchiya, 1972 .

Studies on Aminosugars. XXVII. Synthesis of Several Glycosides Containing (6-Amino-6-deoxy-D-glucopyranosyl)-2-deoxystreptamine

Y. Nishimura, S. Umezawa, T. Tsuchiya, 1971 .

Syntheses of 2',3'-dideoxykanamycin A, 2',3'-dideoxyamikacin and related substances

Yoshihiko Kobayashi, H. Umezawa, S. Umezawa, 1987 .

3'-Deoxyamikacin and 3',4'-dideoxyamikacin and their antibacterial activities.

M. Hamada, H. Umezawa, T. Miyake, 1979, The Journal of antibiotics.

Reactions on methyl 2-deoxy-2-trifluoroacetamido-3-O-trifluoromethylsulfonyl-α-D-glucopyranoside derivatives: formation of ring-contraction compounds

K. Ajito, S. Umezawa, T. Tsuchiya, 1984 .

Synthesis of (3'R)-3'-deoxy-3'-C-nitromethylthymidine.

Y. Takahashi, T. Tsuchiya, Y. Honda, 1995, Carbohydrate research.

Structure of antipain, a new Sakaguchi-positive product of streptomyces.

H. Umezawa, K. Tatsuta, K. Fujimoto, 1972, The Journal of antibiotics.

Study on fluorination-toxicity relationships. Syntheses of 1-N-[(2R,3R)- and (2R,3S)-4-amino-3-fluoro-2-hydroxybutanoyl] derivatives of kanamycins.

Y. Takahashi, C. Ueda, Y. Kobayashi, 1993, Carbohydrate research.

Synthesis of low-toxicity, 5-deoxy-5-fluoro and 5-deoxy-5,5-difluoro derivatives of arbekacin and its analogs, and study of structure-toxicity relationships.

T. Takeuchi, M. Hamada, T. Shitara, 1993, Carbohydrate research.

Synthesis of 5-deoxy-5-fluoro and 5-deoxy-5,5-difluoro derivatives of kanamycin B and its analogs. Study on structure-toxicity relationships.

T. Shitara, S. Umezawa, Y. Kobayashi, 1992, Carbohydrate research.

Synthesis of 3'-deoxy-3'-fluorokanamycin A and 3',4'-dideoxy-3'-fluorokanamycin A.

H. Umezawa, Y. Takahashi, S. Umezawa, 1991, Carbohydrate research.

Synthesis of 3′,4′,6′-Trideoxy-6′-Fluorokanamycin C, 3′,4′-Dideoxy-6′-C-(fluoromethyl)kanamycin B, and Their 1-N-[(S)-4-Amino-2-hydroxybutanoyl] Derivatives

E. Umemura, S. Umezawa, T. Tsuchiya, 1990 .

SYNTHESIS OF 5“-DEOXY-5”-FLUOROLIVIDOMYCIN B

H. Umezawa, T. Torii, S. Umezawa, 1983 .

Synthesis of 5″-Deoxy-5″-fluorolividomycin B

H. Umezawa, T. Torii, S. Umezawa, 1983 .

Syntheses of 3-fluoro derivatives of sporaricin A, 3-epifluoro-, 3-fluoror, and 3,3-difluoro-3-demethoxysporaricin A.

H. Umezawa, T. Torii, S. Umezawa, 1982, The Journal of antibiotics.

Synthesis of 3′-Deoxykanamycin B (Tobramycin)

H. Umezawa, T. Miyake, S. Umezawa, 1976 .

Synthesis of kanamycin-6'-phosphate.

K. Tatsuta, T. Tsuchiya, E. Yamamoto, 1967, The Journal of antibiotics.

STUDIES OF ANTIBIOTICS AND RELATED SUBSTANCES. XXI. THE SYNTHESIS OF DEOXY AND CHLORODEOXY DERIVATIVES OF KANAMYCIN.

S. Umezawa, T. Tsuchiya, 1965, Bulletin of the Chemical Society of Japan.

Synthesis of 2″-acylamido derivatives of 2″-amino-5,2″-dideoxy-5-epi-5-fluorodibekacin and a study on the structures of 5-fluorinated dibekacin analogs by 13C NMR

T. Tsuchiya, R. Kuwahara, 1997 .

Synthesis of 5-deoxy-5-epifluoro derivatives of arbekacin, amikacin, and 1-N-[(S)-4-amino-2-hydroxybutanoyl]tobramycin (study on structure--toxicity relationships).

T. Shitara, E. Umemura, T. Tsuchiya, 1995, Carbohydrate research.

Synthesis of 2"-oxidized derivatives of 5-deoxy-5-epi-5-fluoro-dibekacin and -arbekacin, and study on structure-chemical shift relationships of urethane(or amide)-type NH protons in synthetic intermediates.

Y. Kobayashi, T. Tsuchiya, 1997, Carbohydrate research.

Synthesis of dibekacin analogs containing 3-oxa- and 3-aza-2,3,4-trideoxy-D-glycero-hexopyranose.

T. Tsuchiya, R. Kuwahara, 1996, Carbohydrate research.

Synthesis of 4'-deoxy-4'-fluorokanamycin A and B.

Y. Takahashi, S. Umezawa, T. Tsuchiya, 1992, Carbohydrate Research.

A synthesis of 3',4'-dideoxykanamycin B.

H. Umezawa, T. Miyake, S. Umezawa, 1976, Carbohydrate research.

Synthesis of Low-Toxicity, 5-Deoxy-5-fluoro, and 5-Deoxy-5,5-difluoro Derivatives of Arbekacin and Its Analogs, and Study of Structure- Toxicity Relationships.

T. Takeuchi, M. Hamada, T. Shitara, 1993 .

Synthesis of 3′‐Deoxy‐3′‐fluorokanamycin A* and 3′,4′‐Dideoxy‐3′‐ fluorokanamycin A.

H. Umezawa, Yoshiaki Takahashi, S. Umezawa, 1992 .

Synthesis of 3′,4′,6′‐Trideoxy‐6′‐fluorokanamycin C, 3′,4′‐Dideoxy‐6′‐ C‐(fluoromethyl)kanamycin B, and Their 1‐N‐((S)‐4‐Amino‐2‐ hydroxybutanoyl) Derivatives.

E. Umemura, S. Umezawa, T. Tsuchiya, 1991 .

Synthesis of 1-N-(D-threo- and racemic erythro-3-amino-2-hydroxybutanoyl)-2',3'-dideoxykanamycin A.

E. Umemura, S. Umezawa, T. Tsuchiya, 1988, The Journal of antibiotics.

Transformation of kanamycin a into 3′-deoxykanamycin A

H. Umezawa, S. Umezawa, T. Tsuchiya, 1981 .

Syntheses of 5-Deoxy-, 5,4′-Dideoxy-, 5-Deoxy-5-epichloro-, and 5,4′-Dideoxy-5,4′-diepichlorokanamycin A

T. Miyake, S. Umezawa, T. Tsuchiya, 1983 .

Syntheses of 4′-Deoxykanamycin and 4′-Deoxykanamycin B

H. Umezawa, T. Miyake, S. Umezawa, 1977 .

SYNTHESIS OF 3′‐DEOXYKANAMYCIN B (TOBRAMYCIN)

H. Umezawa, T. Miyake, S. Umezawa, 1977 .

Studies on Aminosugars. XXXV. Syntheses of 3′,4′-Dideoxyneamine and 3′- and 4′-O-Methylneamines

H. Umezawa, S. Umezawa, T. Tsuchiya, 1973 .

Studies on Aminosugars. XXXVI. Syntheses of 3′,4′-Dideoxy-and 3′,4′,5″-Trideoxyribostamycin

H. Umezawa, Toshihisa Suzuki, D. Ikeda, 1973 .

SYNTHESIS OF 3'-DEOXYKANAMYCIN B

H. Umezawa, T. Miyake, S. Umezawa, 1973 .

Synthesis of 3',4'-dideoxy and 3',4',5''-trideoxyribostamycin active against kanamycin-resistant E. coli and P. aeruginosa.

H. Umezawa, D. Ikeda, S. Umezawa, 1972, The Journal of antibiotics.

Synthesis of paromamine.

T. Miyazawa, S. Umezawa, T. Tsuchiya, 1972, The Journal of antibiotics.

Synthesis of 3'.4'-dideoxyneamine active aginst kanamycin-resistant E. coli and P. aeruginosa.

H. Umezawa, S. Umezawa, T. Tsuchiya, 1971, The Journal of antibiotics.

3-deoxygenation of methyl α--glucopyranosides by treatment of their 3--(,-dimethylsulfamoyl) derivatives with sodium metal in liquid ammonia

T. Usui, Masao Yoshida, S. Umezawa, 1979 .

Syntheses of 3,4-Dideoxy-3-enosides and the Corresponding 3,4-Dideoxy Sugars

Y. Okazaki, S. Umezawa, T. Tsuchiya, 1971 .

Studies of antibiotics and related substances. XXXI. The synthesis of kanamycin-6'-phosphate.

K. Tatsuta, S. Umezawa, T. Tsuchiya, 1967, Bulletin of the Chemical Society of Japan.

ACID REVERSION PRODUCTS FROM AMINO-SUGARS AND DEOXYSTREPTAMINE.

S. Umezawa, T. Tsuchiya, H. Fujita, 1964, The Journal of antibiotics.

SYNTHESIS OF DEOXYKANAMYCIN.

S. Umezawa, T. Tsuchiya, S. Iriyama, 1963, The Journal of antibiotics.

Synthesis of 5‐Deoxy‐5‐epifluoro Derivatives of Arbekacin, Amikacin, and 1‐N‐((S)‐4‐Amino‐2‐hydroxybutanoyl)tobramycin (Study on Structure‐ Toxicity Relationships).

T. Shitara, E. Umemura, T. Tsuchiya, 1996 .

Synthesis of 5-deoxy-5-fluoro- and 5-deoxy-5,5-difluoro-netilmicin.

E. Umemura, S. Umezawa, T. Tsuchiya, 1993, Carbohydrate Research.

SYNTHESES OF 3''- AND 4''-O-METHYLENEAMINE

H. Umezawa, S. Umezawa, T. Tsuchiya, 1972 .

Synthesis of 7-O-[2,6-dideoxy-2-fluoro-4-O-(3-fluorotetrahydropyran-2-yl)- alpha-L-talopyranosyl]daunomycinone.

T. Takeuchi, S. Umezawa, Y. Takagi, 1992, Journal of antibiotics (Tokyo. 1968).

Reaction of 2-deoxy-6-O-[2,3-dideoxy-4,6-O-isopropylidene-2,3- (N-tosylepimino)-alpha-D-mannopyranosyl]-4,5-O-isopropylidene-1,3-di-N- tosylstreptamine with potassium hydrogenfluoride.

K. Koga, Y. Kobayashi, T. Tsuchiya, 1992, Carbohydrate Research.

Syntheses of 6'-N-methyl-kanamycin and 3',4'-dideoxy-6'-N-methylkanamycin B active against resistant strains having 6'-N-acetylating enzymes.

H. Umezawa, Y. Nishimura, S. Umezawa, 1972, The Journal of antibiotics.

Syntheses of 6"-Deoxy-6"-fluorokanamycin A, 6"-Deoxy-6"-fluoroamikacin and 1-N-[(R)- and (RS)-3-Amino-2-fluoropropanoyl]kanamycins.

S. Umezawa, Y. Takagi, T. Tsuchiya, 1985 .

Synthesis of 3,4'-dideoxymycaminosyl tylonolide, a novel type of macrolide derivative.

T. Takeuchi, S. Kageyama, S. Umezawa, 1992, Journal of antibiotics (Tokyo. 1968).

Synthesis of 6-deoxydihydrostreptomycin

Yoshihiko Kobayashi, H. Umezawa, T. Kishi, 1982 .

Total synthesis of bleomycin A21)

Y. Umezawa, M. Otsuka, M. Ohno, 1982 .

Improved Syntheses of 3′-Deoxybutirosin A and B

S. Umezawa, T. Tsuchiya, I. Watanabe, 1977 .

Total synthesis of streptomycin.

T. Usui, Y. Takahashi, S. Umezawa, 1974, The Journal of antibiotics.

Structure of (2-amino-2-deoxy-alpha-D-glucosyl)-deoxystreptamine produced by acid reversion.

S. Umezawa, T. Tsuchiya, H. Fujita, 1966, The Journal of antibiotics.

Synthesis of 4'-deoxykanamycin and its resistance to kanamycin phosphotransferase II.

M. Yagisawa, Y. Nishimura, S. Umezawa, 1974, The Journal of antibiotics.

SYNTHESIS OF 3'-DEOXYRIBOSTAMYCIN

Hamao Umezawa, Tsutomu Tsuchiya, Sumio Umezawa, 1973 .

SYNTHESIS OF 3'', 4''-DIDEOXYBUTIROSIN B

M. Hamada, H. Umezawa, D. Ikeda, 1973 .

Facile syntheses of methyl 2-amino-2-deoxyglucopyranosides

T. Usui, T. Kamiya, S. Umezawa, 1979 .

Structural Studies on the Cyclic Carbamate Derivatives of Kanamycin A

S. Umezawa, Y. Takagi, T. Tsuchiya, 1981 .

Syntheses of 6'-C-aminomethyl-3'-deoxyparomamines.

T. Yamaguchi, S. Umezawa, T. Tsuchiya, 1977, The Journal of antibiotics.

Synthesis of a Masked Derivative of 3′-Deoxydihydrostreptobiosamine, a Precursor for the Synthesis of 3″-Deoxydihydrostreptomycin

H. Sano, H. Umezawa, Shigeru Kobayashi, 1977 .

STUDIES ON AMINOSUGARS PART 35, SYNTHESES OF 3′,4′-DIDEOXYNEAMINE AND 3′- AND 4′-O-METHYLNEAMINES

H. Umezawa, S. Umezawa, T. Tsuchiya, 1974 .

A Synthesis of Neamine

S. Umezawa, T. Tsuchiya, Akihiko Harayama, 1979 .

Synthesis of a Lividomycin B Analogue, 5-O-[3-O-(2-Amino-2-deoxy-α-D-grlucopyranosyl)-β-D-ribofuranosyl]-3′-deoxyparomamine

H. Umezawa, S. Umezawa, T. Tsuchiya, 1977 .

Studies on Aminosugars. XXXIV. Synthesis of 4-O- and 6-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2-deoxystreptamine

Y. Nishimura, S. Umezawa, T. Tsuchiya, 1973 .

Reactions of 2-Guanidino-1-cyclohexanol with Ketals and Acetals

H. Sano, S. Umezawa, Y. Takagi, 1976 .

Synthesis of 6′-Amino-1- N -[( S )-4-Amino-2-Hydroxybutyryl]-6′-Deoxylividomycin A

H. Umezawa, A. Ejima, S. Umezawa, 1975 .

STUDIES ON AMINOSUGARS PART 36, SYNTHESES OF 3′,4′-DIDEOXY- AND 3′,4′,5′-TRIDEOXY-RIBOSTAMYCIN

H. Umezawa, Toshihisa Suzuki, D. Ikeda, 1973 .

A synthesis of 2,6-dideoxy-2-fluoro-L-glycopyranose from D-fructose: synthesis of 1,3,4-tri-O-acetyl-2,6-dideoxy-2-fluoro-L-talopyranose

S. Umezawa, Y. Takagi, T. Tsuchiya, 1992 .

Letter: Synthesis of 1-N-((s)-4-amino-2-hydroxybutyryl)-3',4'-dideoxyneamine.

H. Umezawa, D. Ikeda, S. Umezawa, 1973, The Journal of antibiotics.

Letter: Synthesis of 1-N-((s)-4-amino-2-hydroxybutyryl)lividomycin A.

H. Umezawa, S. Umezawa, T. Tsuchiya, 1973, The Journal of antibiotics.

SYNTHESES OF 6''-AMINO-6''-DEOXYLIVI-DOMYCIN B AND 6''-DEOXY-6''-METHYLAMINO- AND 6''-DEOXY-6''-(2-HYDROXYETHYLAMINO)- LIVIDOMYCIN B

H. Umezawa, S. Umezawa, T. Tsuchiya, 1973 .

Synthesis and antitumor activity of 7-O-[2,6-dideoxy-2-fluoro-5-C-(trifluoromethyl)-alpha-L-talopyranosyl]- daunomycinone and -adriamycinone.

K. Nakai, Y. Takagi, T. Tsuchiya, 1999, Carbohydrate research.

Synthesis and antitumor activities of 14-O-acyl derivatives of 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)adriamycinone.

T. Takeuchi, H. Umezawa, K. Komuro, 1988, The Journal of antibiotics.

Syntheses and antitumor activities of 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone.

T. Takeuchi, H. Umezawa, S. Umezawa, 1986, The Journal of antibiotics.

Synthesis of neamine.

K. Tatsuta, S. Umezawa, E. Kitazawa, 1980, The Journal of antibiotics.

Selective methylations of the 2′-hydroxy and C-2 positions of 3-deoxy-5-O-(4-deoxymycaminosyl)tylonolide

S. Kageyama, T. Tsuchiya, 1995 .

Synthesis of 2-C-Methyl Derivatives of 3,4′- Dideoxymycaminosyltylonolide, a Novel Type of 16-Membered Macrolide Antibiotic.

S. Kageyama, T. Tsuchiya, 1995 .

Synthesis of 2-C-methyl derivatives of 3,4'-dideoxymycaminosyltylonolide, a novel type of 16-membered macrolide antibiotic.

S. Kageyama, T. Tsuchiya, 1994, The Journal of antibiotics.

Synthesis of 3-deoxy-3,4-didehydro derivatives of 5-O-mycaminosyltylonolide, 5-O-(4-deoxymycaminosyl) tylonolide, and desmycosin.

S. Kageyama, S. Umezawa, T. Tsuchiya, 1993, The Journal of antibiotics.

Synthesis of 5''-amino-3,5''-dideoxybutirosin A.

M. Hamada, S. Umezawa, T. Tsuchiya, 1978, The Journal of antibiotics.

Synthesis of 3', 3''-dideoxy-butirosin.

M. Hamada, S. Umezawa, T. Tsuchiya, 1978, The Journal of antibiotics.

Synthesis of 3″-epidihydrostreptomycin☆

T. Shitara, T. Tsuchiya, 1982 .

Synthesis of 5-O- and 6-O-Methyldihydrostreptomycin

Yoshihiko Kobayashi, T. Kishi, S. Umezawa, 1985 .

SYNTHESIS OF A MASKED DERIVATIVE OF 3′‐DEOXYDIHYDROSTREPTOBIOSAMINE, A PRECURSOR FOR THE SYNTHESIS OF 3′‐DEOXYDIHYDROSTREPTOMYCIN

H. Sano, H. Umezawa, Shigeru Kobayashi, 1977 .

Synthesis of Di-N-acetyl-di-N-benzyloxycarbonyl-O-cyclohexylidenestreptidine

Yoshikazu Takahashi, S. Umezawa, T. Tsuchiya, 1975 .

1- and 3-deamidino derivatives of dihydrostreptomycin and some 1-N-acyl derivatives.

T. Usui, S. Umezawa, T. Tsuchiya, 1978, The Journal of antibiotics.

Studies on O→N Acyl Migration in O-Acyl-2-deoxystreptamines

T. Miyake, Y. Nishimura, S. Umezawa, 1976 .

SYNTHESIS OF A LIVIDOMYCIN B ANALOG, 5-O-(3-O-(2-AMINO-2-DEOXY-α-D-GLUCOPYRANOSYL)-β-D-RIBOFURANOSYL)-3′-# DEOXYPAROMAMINE

H. Umezawa, S. Umezawa, T. Tsuchiya, 1977 .

SYNTHESIS OF 6′-AMINO-1-N-((S)-4-AMINO-2-HYDROXYBUTYRYL)-6′-DEOXYLIVIDOMYCIN A

H. Umezawa, A. Ejima, S. Umezawa, 1975 .

A new method for N-demethylation of 2-deoxy-2-methylamino-α-d-glucopyranoside derivatives by air oxidation using palladium in aqueous 1,4-dioxane

S. Nishimura, S. Umezawa, T. Tsuchiya, 1983 .

α- and β-hydrogen eliminations in the reactions of some 3-O-triflylglycosides with ′BuOk and pyridine

A. Nemr, T. Tsuchiya, 1997 .

α-hydrogen elimination in some 3- and 4-triflates of α-d-glycopyranosides

A. Nemr, T. Tsuchiya, 1997 .

A new microbial metabolite, sphydrofuran. I. Isolation and the structure of a hydrolysis product.

T. Usui, T. Takeuchi, H. Umezawa, 1971, The Journal of antibiotics.

Synthesis and antitumor activity of 5'-demethyl-5'-trifluoromethyl-daunorubicin and -doxorubicin.

S. Ogawa, K. Nakai, Y. Takagi, 1999, Carbohydrate research.

RETRO-SYNTHETIC MANIPULATION OF BLEOMYCINS

Y. Umezawa, M. Otsuka, M. Ohno, 1982 .

Syntheses of 23-Dialkylamino-23-deoxydemycinosyltylosins and Conformational Study of Mycaminosyl Tylonolide by Nuclear Overhauser Difference Spectroscopy

A. Tanaka, T. Miyake, S. Sakamoto, 1984 .

Syntheses of 4'-deoxy-demycarosyl tylosin and its analogues.

H. Umezawa, S. Umezawa, A. Tanaka, 1981, The Journal of antibiotics.

KF77-AG6, an antipain-related metabolite.

H. Umezawa, K. Tatsuta, K. Fujimoto, 1974, The Journal of antibiotics.

Synthesis and antitumor activity of the 7-O-(2,6-dideoxy-2-fluoro-α-l-talopyranosyl)daunomycinone derivatives modified at C-3′ or C-4′

M. Chang, N. Kobayashi, Y. Takagi, 1998 .

OF ANTIBIOTICS KD 16-U 1 , A NEW METABOLITE OF STREPTOMYCES : ISOLATION AND STRUCTURAL STUDIES

K. Tatsuta, N. Mikami, S. Umezawa, 2006 .

TOTAL SYNTHESIS OF BLEOMYCIN A2

Y. Umezawa, M. Otsuka, M. Ohno, 1982 .

A 5'-(trifluoromethyl)anthracycline glycoside: synthesis of antitumor-active 7-O-(2,6-dideoxy-6,6,6-trifluoro-alpha-L-lyxo-hexopyranosyl) adriamycinone.

T Takeuchi, T. Takeuchi, Y Takagi, 1996, Journal of medicinal chemistry.

Biological activities of new anthracyclines containing fluorine, FAD104 and its metabolites.

T. Takeuchi, S. Kunimoto, K. Komuro, 1990, The Journal of antibiotics.

Biological properties of ME2303 (FAD-104), a new anthracycline.

K. Umezawa, T. Takeuchi, S. Omoto, 1988, Drugs under experimental and clinical research.

Synthesis of 8-O-alkylshikonin(alkannin)s: new ketal formation, tautomerism, and nucleophilic aromatic substitution

T. Tsuchiya, S. Ohmuro, 2002 .